ArticleJournal of cardiovascular development and disease2023
Cardiac Fibrosis and Innervation State in Uncorrected and Corrected Transposition of the Great Arteries: A Postmortem Histological Analysis and Systematic Review.
Article in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Prevalence and Predictors of Impaired Coronary Flow Velocity Reserve in Adolescents After Arterial Switch Operation.Diagnostics (Basel, Switzerland) · 2026Article
- Cardiac Autonomic Function and Atrial Arrhythmias in Adult Patients With a Univentricular Physiology After Fontan Palliation.CJC pediatric and congenital heart disease · 2026Article
- T1 mapping of the right ventricle in congenital heart disease: a focus on pediatrics.Pediatric radiology · 2025Review
- Using machine learning analysis to describe patterns in tissue Doppler and speckle tracking echocardiography in patients with transposition of the great arteries after arterial switch operation.International journal of cardiology. Congenital heart disease · 2025Article
- Histologic changes in systemically loaded right ventricles at time of transplantation.Frontiers in cardiovascular medicine · 2025Article
- Arterial switch operation: A surgical triumph with long-term management challenges.International journal of cardiology. Congenital heart disease · 2024Article
- Coronary coding in dTGA pre- and post-ASO-verification and necessary corrections following adult CMR.European heart journal. Imaging methods and practice · 2024Article
- Late follow-up of neo-aortic dimensions and coronary arteries in adult patients after the arterial switch operation.International journal of cardiology. Congenital heart disease · 2023Article
- Ventricular arrhythmia in congenital heart diseases with a systemic right ventricle.International journal of cardiology. Congenital heart disease · 2023Review
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
In the transposition of the great arteries (TGA), alterations in hemodynamics and oxygen saturation could result in fibrotic remodeling, but histological studies are scarce. We aimed to investigate fibrosis and innervation state in the full spectrum of TGA and correlate findings to clinical literature. Twenty-two human postmortem TGA hearts, including TGA without surgical correction (n = 8), after Mustard/Senning (n = 6), and arterial switch operation (ASO, n = 8), were studied. In newborn uncorrected TGA specimens (1 day-1.5 months), significantly more interstitial fibrosis (8.6% ± 3.0) was observed compared to control hearts (5.4% ± 0.8,
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