Evidence map›Paper›PMID 37102972›Full record

ArticleMicrobiology spectrum2023

Role of the NaHCO

Sook-Ha Fan, Richard A Proctor, Selvi C Ersoy, Adhar C Manna, Ambrose L Cheung, Friedrich Götz, Henry F Chambers, Arnold S Bayer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Phenotypic and genotypic correlates of the sodium bicarbonate-responsive phenotype among methicillin-resistant Staphylococcus aureus isolates from skin and soft-tissue infections.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2025
    Article
  3. Review
  4. Article
  5. International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Sook-Ha FanThe Lundquist Institute, Torrance, California, USA.ORCID 0000-0003-0556-238X
Richard A ProctorDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Selvi C ErsoyThe Lundquist Institute, Torrance, California, USA.ORCID 0000-0002-8792-2061
Adhar C MannaDepartment of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-4055-2489
Ambrose L CheungDepartment of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Friedrich GötzMicrobial Genetics, Interfaculty Institute of Microbiology and Infection Medicine Tübingen, University of Tübingen, Germany.ORCID 0000-0002-2042-0518
Henry F ChambersUCSF School of Medicine, San Francisco, California, USA.
Arnold S BayerThe Lundquist Institute, Torrance, California, USA.
Dartmouth College · USUniversity of California, Los Angeles · USUniversity of Tübingen · DEUniversity of Wisconsin–Madison · US

Funding

Bicarbonate-Mediated Enhancement of Beta-Lactam-MRSA Killing: Mechanisms and Clinical TranslatabilityR01AI146078 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI XIONG, YAN Q. · 2019 to 2023
$1.9M
NIAID NIH HHS R01 AI146078
6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) infections are an increasing concern due to their intrinsic resistance to most standard-of-care β-lactam antibiotics. Recent studies of clinical isolates have documented a novel phenotype, termed NaHCO

Indexed as

Methicillin-Resistant Staphylococcus aureusAnti-Bacterial AgentsBacterial Proteinsbeta-LactamsCarbon DioxideMicrobial Sensitivity TestsOxacillinPhenotypePyridinesStaphylococcus aureusSulfonamides3-mercaptopyridine-2-sulfonamideAnti-Bacterial AgentsBacterial Proteinsbeta-LactamsCarbon DioxideOxacillinPyridinesSulfonamidesbicarbonate transporterCO2membrane potential-generating system ABCmethicillin-resistant Staphylococcus aureusMpsABCMRSAsodium bicarbonateβ-lactams

Identifiers

PMID37102972
PMCPMC10269494
OpenAlexW4367174254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.