Evidence map›Paper›PMID 37102914›Full record

ReviewGels (Basel, Switzerland)2023

The Use of Hydrogel-Based Materials for Radioprotection.

Yang Li, Han Liu, Yaqun Ding, Wanyu Li, Yuansong Zhang, Shenglin Luo, Qiang Xiang

Open access · goldAbstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yang LiCenter of emergency, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Han LiuCenter of emergency, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Yaqun DingCenter of emergency, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Wanyu LiInstitute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Yuansong ZhangCenter of emergency, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Shenglin LuoInstitute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, China.ORCID 0000-0002-0804-9891
Qiang XiangCenter of emergency, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Army Medical University · CN

Funding

Chongqing Talents Project cstc2021ycjhbgzxm0123Intramural Research Project Grants No. AEP17J001National Natural Science Foundation of China No. 82173457
6 · The paper itself

Abstract

Major causes of the radiation-induced disease include nuclear accidents, war-related nuclear explosions, and clinical radiotherapy. While certain radioprotective drug or bioactive compounds have been utilized to protect against radiation-induced damage in preclinical and clinical settings, these strategies are hampered by poor efficacy and limited utilization. Hydrogel-based materials are effective carriers capable of enhancing the bioavailability of compounds loaded therein. As they exhibit tunable performance and excellent biocompatibility, hydrogels represent promising tools for the design of novel radioprotective therapeutic strategies. This review provides an overview of common approaches to radioprotective hydrogel preparation, followed by a discussion of the pathogenesis of radiation-induced disease and the current states of research focused on using hydrogels to protect against these diseases. These findings ultimately provide a foundation for discussions of the challenges and future prospects associated with the use of radioprotective hydrogels.

Indexed as

hydrogelsradiation injuryradioprotection

Identifiers

PMID37102914
PMCPMC10137482
OpenAlexW4362600824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.