Evidence map›Paper›PMID 37102904›Full record

ReviewGels (Basel, Switzerland)2023

Advances in Nanogels for Topical Drug Delivery in Ocular Diseases.

Yongkang Wu, Qing Tao, Jing Xie, Lili Lu, Xiuli Xie, Yang Zhang, Yong Jin

Open access · goldAbstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
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  4. Current perspectives in tackling glaucoma blindness.Indian journal of ophthalmology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yongkang WuSchool of Pharmacy, Anhui Medical University, No. 81 Meishan Road, Shushan District, Hefei 230032, China.ORCID 0009-0003-8126-3581
Qing TaoSchool of Pharmacy, Anhui Medical University, No. 81 Meishan Road, Shushan District, Hefei 230032, China.
Jing XieSchool of Pharmacy, Anhui Medical University, No. 81 Meishan Road, Shushan District, Hefei 230032, China.
Lili LuSchool of Pharmacy, Anhui Medical University, No. 81 Meishan Road, Shushan District, Hefei 230032, China.
Xiuli XieSchool of Pharmacy, Anhui Medical University, No. 81 Meishan Road, Shushan District, Hefei 230032, China.
Yang ZhangSchool of Pharmacy, Anhui Medical University, No. 81 Meishan Road, Shushan District, Hefei 230032, China.
Yong JinSchool of Pharmacy, Anhui Medical University, No. 81 Meishan Road, Shushan District, Hefei 230032, China.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotechnology has accelerated the development of the pharmaceutical and medical technology fields, and nanogels for ocular applications have proven to be a promising therapeutic strategy. Traditional ocular preparations are restricted by the anatomical and physiological barriers of the eye, resulting in a short retention time and low drug bioavailability, which is a significant challenge for physicians, patients, and pharmacists. Nanogels, however, have the ability to encapsulate drugs within three-dimensional crosslinked polymeric networks and, through specific structural designs and distinct methods of preparation, achieve the controlled and sustained delivery of loaded drugs, increasing patient compliance and therapeutic efficiency. In addition, nanogels have higher drug-loading capacity and biocompatibility than other nanocarriers. In this review, the main focus is on the applications of nanogels for ocular diseases, whose preparations and stimuli-responsive behaviors are briefly described. The current comprehension of topical drug delivery will be improved by focusing on the advances of nanogels in typical ocular diseases, including glaucoma, cataracts, dry eye syndrome, and bacterial keratitis, as well as related drug-loaded contact lenses and natural active substances.

Indexed as

contact lensesdrug delivery systemsnanogelsnatural polymersocular diseases

Identifiers

PMID37102904
PMCPMC10137933
OpenAlexW4362580683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.