Evidence map›Paper›PMID 37102787›Full record

ArticleHead & neck2023

Update on adherence to guidelines for time to initiation of postoperative radiation for head and neck squamous cell carcinoma.

F Jeffrey Lorenz, Sean S Mahase, Joseph Miccio, Tonya S King, Sandeep Pradhan, Neerav Goyal

Open access · hybridAbstract read
In one paragraph

Article in Head & neck, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Factors Associated with Head and Neck Cancer Postoperative Radiotherapy Delays: A Systematic Review and Meta-analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Pooled it
  2. Trial
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  4. Article
  5. Comment on: "Prognostic Significance of Surgery-to-Postoperative Radiation Therapy Interval (S-PORT) and Total Treatment Package Time (TPT) in HNSCC".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
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  7. Implementation Mapping to Identify Strategies to Increase Timely Postoperative Radiotherapy Initiation for Head/Neck Cancer.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
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  9. The prognosis and treatment of newly diagnosed bone metastasis of head and neck squamous cell cancer: an analysis of racial disparity.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
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  14. A Targeted Approach to Dental Treatment for Patients Prior To and After Head and Neck Radiation.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

F Jeffrey LorenzCollege of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.ORCID 0000-0001-5902-7054
Sean S MahaseCollege of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
Joseph MiccioCollege of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
Tonya S KingDepartment of Public Health Sciences, Penn State Hershey Medical Center, Hershey, Pennsylvania, USA.
Sandeep PradhanDepartment of Public Health Sciences, Penn State Hershey Medical Center, Hershey, Pennsylvania, USA.
Neerav GoyalCollege of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.ORCID 0000-0001-7783-1097
Pennsylvania State University · USPenn State Milton S. Hershey Medical Center · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
NCATS NIH HHS UL1 TR002014
6 · The paper itself

Abstract

backgroundA prior study reported that over half of patients with HNSCC initiated PORT after 6 weeks from surgery during 2006-2014. In 2022, the CoC released a quality metric for patients to initiate PORT within 6 weeks. This study provides an update on time to PORT in recent years.

methodsThe NCDB and TriNetX Research Network were queried to identify patients with HNSCC who received PORT during 2015-2019 and 2015-2021, respectively. Treatment delay was defined as initiating PORT beyond 6 weeks after surgery.

resultsIn NCDB, PORT was delayed for 62% of patients. Predictors of delay included age >50, female sex, black race, nonprivate insurance/uninsured status, lower education, oral cavity site, negative surgical margins, increased postoperative length of stay, unplanned hospital readmissions, IMRT radiation modality, treatment at an academic hospital or in the Northeast, and surgery and radiation at different facilities. In TriNetX, 64% experienced treatment delay. Additional associations with prolonged time to treatment included never married/divorced/widowed marital status, major surgery (neck dissection/free flaps/laryngectomy), and gastrostomy/tracheostomy dependence.

conclusionsThere continue to be challenges to timely initiation of PORT.

Indexed as

Guideline AdherenceHead and Neck NeoplasmsPractice Guidelines as TopicRadiotherapy, AdjuvantSquamous Cell Carcinoma of Head and NeckAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeck DissectionPostoperative CareTime-to-Treatmenthead and neck cancerhead and neck squamous cell carcinomapostoperative radiationquality caretreatment delay

Identifiers

PMID37102787
PMCPMC10797635
OpenAlexW4367174883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.