Evidence map›Paper›PMID 37102735›Full record

ArticleJournal of the American Society for Mass Spectrometry2023

Nonenzymatic Posttranslational Modifications and Peptide Cleavages Observed in Peptide Epimers.

Connor C Long, Aleksandra Antevska, David H Mast, Samuel Okyem, Jonathan V Sweedler, Thanh D Do

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Connor C LongDepartment of Biochemistry, Cellular, and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996, United States.
Aleksandra AntevskaDepartment of Chemistry, University of Tennessee, Knoxville, Tennessee 37996, United States.ORCID 0000-0003-2669-2853
David H MastDepartment of Chemistry and the Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0001-5202-8708
Samuel OkyemDepartment of Chemistry and the Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0001-8227-7545
Jonathan V SweedlerDepartment of Chemistry and the Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0003-3107-9922
Thanh D DoDepartment of Chemistry, University of Tennessee, Knoxville, Tennessee 37996, United States.ORCID 0000-0002-1978-4365
University of Illinois Urbana-Champaign · USUniversity of Tennessee at Knoxville · US

Funding

The UIUC Neuroproteomics Center on Cell-Cell SignalingP30DA018310 · NIDA · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI Jonathan V. Sweedler · 2004 to 2026
$24.9M
SUBCELLULAR CHARACTERIZATION OF NEUROTRANSMITTERSR01NS031609 · NINDS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI SWEEDLER, JONATHAN V. · 1998 to 2022
$6.2M
NIDA NIH HHS P30 DA018310NINDS NIH HHS R01 NS031609
6 · The paper itself

Abstract

Posttranslational modifications (PTMs) play vital roles in cellular homeostasis and are implicated in various pathological conditions. This work uses two ion mobility spectrometry-mass spectrometry (IMS-MS) modalities, drift-tube IMS (DT-IMS) and trapped IMS (TIMS), to characterize three important nonenzymatic PTMs that induce no mass loss: l/d isomerization, aspartate/isoaspartate isomerization, and

Indexed as

Aspartic AcidIsoaspartic AcidAmino Acid SequenceIsomerismPeptidesProlineTandem Mass SpectrometryAspartic AcidIsoaspartic AcidPeptidesProlineasparagine deamidationcis/trans proline isomerizationIsoAsp formationmass spectrometryposttranslational modifications

Identifiers

PMID37102735
PMCPMC10524105
OpenAlexW4367174372

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.