ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023
Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- A systematic review of microgravity on reproductive systems: Implications for space biology and human health.iScience · 2026Review
- Mitochondrial capacities and quality control following short- and long-term weight restoration after simulated anorexia nervosa.Experimental physiology · 2025Article
- Divergent alterations in the skeletal muscle and serum proteome in a rodent model of anorexia nervosa and weight recovery.Research square · 2025Article
- Changes in muscle strength and moderators of protein turnover in a rodent model of anorexia nervosa and recovery.bioRxiv : the preprint server for biology · 2025Article
- Electrical impedance myography as a marker of muscle mass in rats with simulated Anorexia Nervosa.Journal of electrical bioimpedance · 2025Article
- Sex-specific cardiovascular adaptations to simulated microgravity in Sprague-Dawley rats.NPJ microgravity · 2024Article
- Synergistic interplay between radiation and microgravity in spaceflight-related immunological health risks.Immunity & ageing : I & A · 2024Review
- Adaptation to full weight-bearing following disuse in rats: The impact of biological sex on musculoskeletal recovery.Physiological reports · 2024Article
- Sex differences in muscle health in simulated micro- and partial-gravity environments in rats.Sports medicine and health science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle strength in micro- and partial-gravity environments (e.g., the Moon or Mars) is not fully understood. The purpose of this study was to determine the influence of gonadectomy (castration/ovariectomy) on progression of muscle atrophy in both micro- and partial-gravity environments in male and female rats. Male and female Fischer rats (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.