Evidence map›Paper›PMID 37102128›Full record

ArticleFrontiers in nutrition2023

Association between fatty acids intake and bone mineral density in adults aged 20-59: NHANES 2011-2018.

Ze-Bin Fang, Gao-Xiang Wang, Gui-Zhang Cai, Peng-Xiang Zhang, De-Liang Liu, Shu-Fang Chu, Hui-Lin Li, Hing-Xia Zhao

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Fatty acid dietary intakes and blood concentrations in relation to hip fracture risk in adults: a systematic review and meta-analysis of prospective cohort studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ze-Bin FangThe Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, China.
Gao-Xiang WangDepartment of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.
Gui-Zhang CaiThe Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, China.
Peng-Xiang ZhangThe Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, China.
De-Liang LiuDepartment of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.
Shu-Fang ChuDepartment of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.
Hui-Lin LiDepartment of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.
Hing-Xia ZhaoDepartment of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have investigated the link between fatty acid intake and bone mineral density (BMD), but the results are controversial. This study aims to examine the relationship between fatty acid intake and BMD in adults aged 20-59. Methods: The association between fatty acid consumption and BMD was analyzed using a weighted multiple linear regression model with National Health and Nutrition Examination Survey data from 2011 to 2018. The linearity relationship and saturation value of the connection between fatty acid consumption and BMD were assessed by fitting a smooth curve and a saturation effect analysis model. Results: The study included 8,942 subjects. We found a significant positive correlation between the consumption of saturated fatty acids, monounsaturated fatty acids (MUFAs), and polyunsaturated fatty acids and BMD. In subgroup analyses that were stratified by gender and race, this association was still shown to be significant. Based on the smooth curve and saturation effect analysis, we found no saturation effect for the three fatty acids and total BMD. However, there was a turning point (20.52 g/d) between MUFAs intake and BMD, and only MUFAs intake >20.52 g/d showed a positive correlation between MUFAs and BMD. Conclusion: We found that fatty acid intake is beneficial for bone density in adults. Therefore, according to our findings, it is recommended that adults consume moderate amounts of fatty acids to ensure adequate bone mass but not metabolic diseases.

Indexed as

bone mineral densitymonounsaturated fatty acidsNHANESnutritionpolyunsaturated fatty acidssaturated fatty acids

Identifiers

PMID37102128
PMCPMC10123400

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.