Evidence map›Paper›PMID 37101944›Full record

ArticleCardiovascular digital health journal2023

Artificial intelligence-enabled electrocardiogram to distinguish atrioventricular re-entrant tachycardia from atrioventricular nodal re-entrant tachycardia.

Arunashis Sau, Safi Ibrahim, Daniel B Kramer, Jonathan W Waks, Norman Qureshi, Michael Koa-Wing, Daniel Keene, Louisa Malcolme-Lawes, David C Lefroy, Nicholas W F Linton and 7 more

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular digital health journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. State of the Art of Artificial Intelligence in Clinical Electrophysiology in 2025: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), and the ESC Working Group on E-Cardiology.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Arunashis SauNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Safi IbrahimNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Daniel B KramerNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Jonathan W WaksHarvard-Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Norman QureshiNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Michael Koa-WingDepartment of Cardiology, Imperial College Healthcare NHS Trust, London, United Kingdom.
Daniel KeeneNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Louisa Malcolme-LawesDepartment of Cardiology, Imperial College Healthcare NHS Trust, London, United Kingdom.
David C LefroyDepartment of Cardiology, Imperial College Healthcare NHS Trust, London, United Kingdom.
Nicholas W F LintonNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Phang Boon LimNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Amanda VarnavaDepartment of Cardiology, Imperial College Healthcare NHS Trust, London, United Kingdom.
Zachary I WhinnettNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Prapa KanagaratnamNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Danilo MandicDepartment of Electrical and Electronic Engineering, Imperial College London, London, United Kingdom.
Nicholas S PetersNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Fu Siong NgNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Imperial College Healthcare NHS Trust · GBBeth Israel Deaconess Medical Center · USImperial College London · GB

Funding

British Heart Foundation FS/CRTF/21/24183British Heart Foundation RG/F/22/110078
6 · The paper itself

Abstract

Background: Accurately determining arrhythmia mechanism from a 12-lead electrocardiogram (ECG) of supraventricular tachycardia can be challenging. We hypothesized a convolutional neural network (CNN) can be trained to classify atrioventricular re-entrant tachycardia (AVRT) vs atrioventricular nodal re-entrant tachycardia (AVNRT) from the 12-lead ECG, when using findings from the invasive electrophysiology (EP) study as the gold standard. Methods: We trained a CNN on data from 124 patients undergoing EP studies with a final diagnosis of AVRT or AVNRT. A total of 4962 5-second 12-lead ECG segments were used for training. Each case was labeled AVRT or AVNRT based on the findings of the EP study. The model performance was evaluated against a hold-out test set of 31 patients and compared to an existing manual algorithm. Results: The model had an accuracy of 77.4% in distinguishing between AVRT and AVNRT. The area under the receiver operating characteristic curve was 0.80. In comparison, the existing manual algorithm achieved an accuracy of 67.7% on the same test set. Saliency mapping demonstrated the network used the expected sections of the ECGs for diagnoses; these were the QRS complexes that may contain retrograde P waves. Conclusion: We describe the first neural network trained to differentiate AVRT from AVNRT. Accurate diagnosis of arrhythmia mechanism from a 12-lead ECG could aid preprocedural counseling, consent, and procedure planning. The current accuracy from our neural network is modest but may be improved with a larger training dataset.

Indexed as

AblationArtificial intelligenceAtrioventricular nodal re-entrant tachycardiaAtrioventricular re-entrant tachycardiaElectrocardiogramElectrophysiology studyMachine learning

Identifiers

PMID37101944
PMCPMC10123507
OpenAlexW4318567359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.