Evidence map›Paper›PMID 37101805›Full record

ArticlePulmonary circulation2023

Clare C Prohaska, Xu Zhang, Tae-Hwi L Schwantes-An, Robert S Stearman, Stanley Hooker, Rick A Kittles, Micheala A Aldred, Katie A Lutz, Michael W Pauciulo, William C Nichols and 3 more

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. [Research progress on bioinformatics in pulmonary arterial hypertension].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Review
  4. LA-GEM: imputation of gene expression with incorporation of Local Ancestry.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2024
    Article
  5. Pulmonary circulation · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Clare C ProhaskaDivision of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine Indiana University Indianapolis Indiana USA.ORCID 0000-0002-9097-5762
Xu ZhangDivision of Hematology and Oncology, Department of Medicine University of Illinois at Chicago Chicago Illinois USA.
Tae-Hwi L Schwantes-AnDepartment of Medical and Molecular Genetics Indiana University Indianapolis Indiana USA.
Robert S StearmanDepartment of Medicine Indiana University Indianapolis Indiana USA.
Stanley HookerDivision of Health Equities, Department of Population Sciences City of Hope Duarte California USA.
Rick A KittlesDepartment of Community Health and Preventive Medicine Morehouse School of Medicine Atlanta Georgia USA.
Micheala A AldredDivision of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine Indiana University Indianapolis Indiana USA.
Katie A LutzDivision of Human Genetics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine Cincinnati Ohio USA.
Michael W PauciuloDivision of Human Genetics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine Cincinnati Ohio USA.
William C NicholsDivision of Human Genetics, Department of Pediatrics, Cincinnati Children's Hospital Medical Center University of Cincinnati College of Medicine Cincinnati Ohio USA.
Ankit A DesaiKrannert Institute of Cardiology, Division of Cardiovascular Medicine, Department of Medicine Indiana University Indianapolis Indiana USA.
Victor R GordeukDivision of Hematology and Oncology, Department of Medicine University of Illinois at Chicago Chicago Illinois USA.
Roberto F MachadoDivision of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine Indiana University Indianapolis Indiana USA.
Indiana University Indianapolis · USCincinnati Children's Hospital Medical Center · USUniversity of Illinois Chicago · USCity of Hope · USMorehouse School of Medicine · US

Funding

National Biological Sample and Data Repository for PAHR24HL105333 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI NICHOLS, WILLIAM C · 2012 to 2016
$10.1M
Vascular Targeting Genomic & Genetic Strategies for Acute Chest SyndromeR01HL111656 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI Roberto F. Machado · 2013 to 2026
$7.9M
Genomics of Pulmonary Vascular DiseaseR35HL140019 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI ALDRED, MICHEALA A · 2018 to 2024
$5.6M
Novel mechanisms of obliterative pulmonary vascular remodeling and sever pulmonary arterial hypertensionR01HL133951 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ZHAO, YOU-YANG · 2016 to 2024
$4.9M
Role of Sphingolipid Pathways in the Pathobiology of PAHR01HL127342 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MACHADO, ROBERTO F., NATARAJAN, VISWANATHAN · 2016 to 2023
$4.5M
IU Training Program in Molecular Physiology and Clinical Mechanisms of Lung DiseaseT32HL091816 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Erick Forno, Roberto F. Machado · 2009 to 2026
$4.3M
Risk stratification in pulmonary arterial hypertension: Intersection of OMICs and longitudinal phenotypes through the PAH BiobankR01HL160941 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI DESAI, ANKIT A, NICHOLS, WILLIAM C · 2022 to 2025
$3.2M
NAD-dependent Signaling and Pulmonary Vascular Remodeling in PAHR01HL158108 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI MACHADO, ROBERTO F. · 2022 to 2025
$2.9M
Pathogenic Role of IL-18 in Sickle Cell Cardiomyopathy and Inducible Ventricular TachycardiaR01HL136603 · NHLBI · UNIVERSITY OF ARIZONA · PI DESAI, ANKIT A · 2017 to 2021
$2.4M
NHLBI NIH HHS R01 HL111656NHLBI NIH HHS R01 HL127342NHLBI NIH HHS R01 HL133951NHLBI NIH HHS R01 HL136603NHLBI NIH HHS R01 HL158108NHLBI NIH HHS R01 HL160941NHLBI NIH HHS R24 HL105333NHLBI NIH HHS R35 HL140019NHLBI NIH HHS T32 HL091816
6 · The paper itself

Abstract

Pulmonary hypertension (PH) is associated with significant morbidity and mortality. RASA3 is a GTPase activating protein integral to angiogenesis and endothelial barrier function. In this study, we explore the association of RASA3 genetic variation with PH risk in patients with sickle cell disease (SCD)-associated PH and pulmonary arterial hypertension (PAH).

Indexed as

pulmonary arterial hypertensionRASA3sickle cell disease‐associated pulmonary hypertension

Identifiers

PMID37101805
PMCPMC10124178
OpenAlexW4365451948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.