Evidence map›Paper›PMID 37101737›Full record

ArticleERJ open research2023

Short-acting β

Ann Morgan, Ekaterina Maslova, Constantinos Kallis, Ian Sinha, Graham Roberts, Trung N Tran, Ralf J P van der Valk, Jennifer K Quint

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Ann MorganNHLI, Imperial College London, London, UK.ORCID https://orcid.org/0000-0003-4794-0860
Ekaterina MaslovaBioPharmaceutical Medical, AstraZeneca, Cambridge, UK.
Constantinos KallisNHLI, Imperial College London, London, UK.
Ian SinhaAlder Hey Children's Hospital, Liverpool, UK.
Graham RobertsUniversity of Southampton Faculty of Medicine, Southampton, UK.ORCID https://orcid.org/0000-0003-2252-1248
Trung N TranEpidemiology, AstraZeneca, Gaithersburg, MD, USA.
Ralf J P van der ValkBioPharmaceutical Medical, AstraZeneca, Cambridge, UK.
Jennifer K QuintNHLI, Imperial College London, London, UK.ORCID https://orcid.org/0000-0003-0149-4869
Imperial College London · GBAstraZeneca (United Kingdom) · GBAstraZeneca (United States) · USUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prescription of three or more short-acting β Methods: This study analysed data on children and adolescents with asthma in three age cohorts: 1‒5 years, 6‒11 years and 12‒17 years from the Clinical Practice Research Datalink Aurum database for the period 1 January 2007 to 31 December 2019. Associations between SABA prescriptions (three or more Results: Overall 48 560, 110 091 and 111 891 paediatric patients with asthma were aged 1‒5, 6‒11 and 12‒17 years, respectively. During the baseline period, 22 423 (46.2%), 42 137 (38.3%) and 40 288 (36.0%) in these three age cohorts, respectively, were prescribed three or more SABA canisters per year. Across all age ranges, the rate of future asthma exacerbations in those prescribed three or more Conclusion: In children, higher SABA prescriptions at baseline were associated with increased future exacerbation rates. These findings highlight the need for monitoring prescription of three or more SABA canisters per year to identify children with asthma at risk of exacerbations.

Identifiers

PMID37101737
PMCPMC10123517
OpenAlexW4323668868

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.