Evidence map›Paper›PMID 37101307›Full record

ArticleBMC endocrine disorders2023

Pituitary adenoma consistency affects postoperative hormone function: a retrospective study.

Dario De Alcubierre, Giulia Puliani, Alessia Cozzolino, Valeria Hasenmajer, Marianna Minnetti, Valentina Sada, Valentina Martines, Antonella Zaccagnino, Andrea Gennaro Ruggeri, Riccardo Pofi and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC endocrine disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Dario De AlcubierreDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Giulia PulianiOncological Endocrinology Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Alessia CozzolinoDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Valeria HasenmajerDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Marianna MinnettiDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Valentina SadaDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Valentina MartinesNeuroradiology Division, Sapienza University of Rome, Rome, Italy.
Antonella ZaccagninoDepartment of Neurology and Psychiatry-Neurosurgery Unit, Sapienza University of Rome, Rome, Italy.
Andrea Gennaro RuggeriDepartment of Neurology and Psychiatry-Neurosurgery Unit, Sapienza University of Rome, Rome, Italy.
Riccardo PofiOxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, UK.
Emilia Sbardella *Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy. emi.sbardella@uniroma1.it.
Mary Anna Venneri *Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy. maryanna.venneri@uniroma1.it.
Sapienza University of Rome · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITOxford Centre for Diabetes, Endocrinology and Metabolism · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTumor consistency recently emerged as a key factor in surgical planning for pituitary adenomas, but its impact on postoperative endocrine function is still unclear. Our study aimed to evaluate the impact of tumor consistency on the development of postoperative pituitary deficiencies.

methodsSingle-center, retrospective analysis of consecutive pituitary surgeries performed between January 2017 and January 2021 at Policlinico Umberto I in Rome. All patients underwent radiological and biochemical evaluations at baseline, and hormone assessments 3 and 6 months after pituitary surgery. Postoperative MRI studies were used to determine resection rates following surgery. Data on tumor consistency, macroscopic appearance, neurosurgical approach, and intraoperative complications were collected.

resultsFifty patients [24 women, mean age 57 ± 13 years, median tumor volume 4800 mm

conclusionsTumor consistency might provide useful information about postoperative pituitary function, likely due to its impact on surgical procedures. Further prospective studies with larger cohorts are needed to confirm our preliminary findings.

Indexed as

AdenomaPituitary NeoplasmsAdultAgedFemaleHormonesHumansMaleMiddle AgedPostoperative ComplicationsProspective StudiesRetrospective StudiesTreatment OutcomeHormonesHypopituitarismPituitary adenomaPostoperative pituitary functionTumor consistency

Identifiers

PMID37101307
PMCPMC10131333
OpenAlexW4367053749

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.