Trial reportBMC ophthalmology2023
Comparison of endothelial cell loss in diabetic patients after conventional phacoemulsification and femtosecond laser-assisted cataract surgery.
Trial report in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- The Eight‑Chop Technique in Cataract Surgery: A Conceptual and Narrative Review of a Segmentation‑First Strategy.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Comparison of Clinical Outcomes Between Femtosecond Laser-assisted Cataract Surgery and Phacoemulsification in Patients with Diabetes: A Systematic Review.Journal of ophthalmic & vision research · 2026Article
- Visual Outcomes and Complication Profiles of Phacoemulsification in Diabetic Versus Non-diabetic Patients.Cureus · 2026Review
- Corneal Endothelial Cell Loss Following Cataract Surgery in Patients with Type 2 Diabetes Mellitus: A Comprehensive Review.Biomedicines · 2025Review
- Micro-interventional pre-treatment for nucleus disassembly in the setting of non-cavitating sonic lensectomy: real-world evidence study in 512 cases.BMC ophthalmology · 2025Article
- Corneal Endothelial Changes After Phacoemulsification Using the Eight-Chop Technique in Diabetic Eyes.Journal of personalized medicine · 2025Article
- Corneal Endothelial Cell Loss in Shallow Anterior Chamber Eyes After Phacoemulsification Using the Eight-Chop Technique.Journal of clinical medicine · 2025Article
- Minimizing Endothelial Cell Loss in Hard Nucleus Cataract Surgery: Efficacy of the Eight-Chop Technique.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aims to comparatively evaluate the morphological changes of the cornea after phacoemulsification (PHACO) and femtosecond laser-assisted cataract surgery (FLACS) without intercurrences in patients with type 2 diabetes mellitus.
methodsA total of 95 diabetic patients with moderate cataracts (N2 + and N3+), 47 undergoing PHACO and 48 undergoing FLACS, were selected randomly for the study. Surgeries were performed by a single surgeon between July 2021 and December 2021. Cumulative dissipated energy (CDE) and total balanced saline solution (BSS) data were obtained at the end of each surgery. Changes in corneal endothelial cell density (ECD) and central corneal thickness (CCT) at three months postoperatively were investigated.
resultsAfter three months, evidence is lacking between groups in the CCT measures; the difference was neither statistically nor clinically relevant. However, for ECD, a significant and clinically significant difference was found; if all patients were treated with laser, the mean ECD would be 423.55 greater (RSE: 86.09; p-value < 0.001; 95% CI: 254.81-592.29) than the ECD potential means of 1656.423 among the conventional group (RSE: 74.90; p-value < 0.001; 95% CI: 1509.62-1803.23).
conclusionsDiabetic patients under treatment with moderate cataracts may predispose themselves to a more significant loss of endothelial cells after conventional phacoemulsification than femtosecond laser-assisted cataract surgery.
trial registrationIt was registered at The Brazilian Registry of Clinical Trials (ReBEC) with the code RBR-6d8whb5 (UTN code: U1111-1277-6020) on 17/05/2022.
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