ArticleBMC microbiology2023
Optimization of fermentation conditions for surfactin production by B. subtilis YPS-32.
Article in BMC microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Secondary Metabolite Biosynthesis and Regulatory Role of Sucrose inMicroorganisms · 2026Review
- Optimized Fermentation of EndophyticMicroorganisms · 2026Article
- Biocontrol potential and mechanism of an endophyticMicrobiology spectrum · 2026Article
- Promoter Engineering of the Surfactin Operon Enhances Surfactin Production in the Environmental Strain Bacillus subtilis RI4914.Current microbiology · 2026Article
- Antimicrobial Peptides, Bacteriocins and Mycocins as Natural Antimicrobials: Applications in Food Safety, Agriculture and Healthcare.Antibiotics (Basel, Switzerland) · 2026Review
- Molecular mechanisms and applications of antimicrobial secondary metabolites ofApplied and environmental microbiology · 2026Review
- Development of surfactin-based nanocarrier for targeted doxorubicin delivery.Scientific reports · 2026Article
- Article
- Attenuated Bacteria-Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Fermentation Conditions and Wettable Powder Formulation of Biocontrol AgentMicroorganisms · 2026Article
- Novel antifungal metabolites from Bacillus velezensis XYDY-1 effectively control peanut Cylindrocladium black rot caused by Calonectria ilicicola.BMC microbiology · 2026Article
- Two EngineeredBiology · 2026Article
- Optimization of fermentation conditions and extracellular metabolic profiling of Streptomyces rochei strain W71.BMC microbiology · 2025Article
- Improvement of neutral protease activity ofJournal of Zhejiang University. Science. B · 2025Article
- Improving the bacillomycin L production in Bacillus amyloliquefaciens by atmospheric and room-temperature plasma combined with Box-Behnken design.Microbial cell factories · 2025Article
- Optimization of fermentation conditions for enhanced acetylcholine and biomass production of Lactiplantibacillus plantarum AM2 using the Taguchi approach.BMC microbiology · 2025Article
- Development of Composite Microbial Products for Managing Pine Wilt Disease in Infected Wood Stumps.Microorganisms · 2024Article
- Preparation of PLA Nanoparticles and Study of Their Influencing Factors.Molecules (Basel, Switzerland) · 2024Article
- Optimization of Antioxidant Activity of Compounds Generated during Ginseng Extract Fermentation Supplemented withMolecules (Basel, Switzerland) · 2024Article
- Genomic insights into antimicrobial potential and optimization of fermentation conditions of pig-derivedFrontiers in microbiology · 2023Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurfactin produced by microbial fermentation has attracted increasing attention because of its low toxicity and excellent antibacterial activity. However, its application is greatly limited by high production costs and low yield. Therefore, it is important to produce surfactin efficiently while reducing the cost. In this study, B. subtilis strain YPS-32 was used as a fermentative strain for the production of surfactin, and the medium and culture conditions for the fermentation of B. subtilis YPS-32 for surfactin production were optimized.
resultsFirst, Landy 1 medium was screened as the basal medium for surfactin production by B. subtilis strain YPS-32. Then, using single-factor optimization, the optimal carbon source for surfactin production by B. subtilis YPS-32 strain was determined to be molasses, nitrogen sources were glutamic acid and soybean meal, and inorganic salts were KCl, K
conclusionIn this study, the fermentation process of surfactin production by B. subtilis YPS-32 was improved by using a combination of single-factor tests and response surface methodology for test optimization, which laid the foundation for its industrial development and application.
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