Evidence map›Paper›PMID 37100893›Full record

ArticleNPJ digital medicine2023

Assessing nocturnal scratch with actigraphy in atopic dermatitis patients.

Ju Ji, Jordan Venderley, Hui Zhang, Mengjue Lei, Guangchen Ruan, Neel Patel, Yu-Min Chung, Regan Giesting, Leah Miller

Open access · goldAbstract read
In one paragraph

Article in NPJ digital medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Current research landscape and future prospects of in silico modeling approaches for atopic dermatitis.JID innovations : skin science from molecules to population health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ju JiEli Lilly & Company, INc., Indianapolis, IN, USA. ju20.stats@gmail.com.ORCID http://orcid.org/0000-0001-7281-1636
Jordan VenderleyEli Lilly & Company, INc., Indianapolis, IN, USA.
Hui ZhangEli Lilly & Company, INc., Indianapolis, IN, USA.ORCID http://orcid.org/0000-0002-3037-3604
Mengjue LeiEli Lilly & Company, INc., Indianapolis, IN, USA.
Guangchen RuanEli Lilly & Company, INc., Indianapolis, IN, USA.
Neel PatelEli Lilly & Company, INc., Indianapolis, IN, USA.ORCID http://orcid.org/0009-0002-0101-2321
Yu-Min ChungEli Lilly & Company, INc., Indianapolis, IN, USA.
Regan GiestingEli Lilly & Company, INc., Indianapolis, IN, USA.
Leah MillerEli Lilly & Company, INc., Indianapolis, IN, USA.
Eli Lilly (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nocturnal scratch is one major factor leading to impaired quality of life in atopic dermatitis (AD) patients. Therefore, objectively quantifying nocturnal scratch events aids in assessing the disease state, treatment effect, and AD patients' quality of life. In this paper, we describe the use of actigraphy, highly predictive topological features, and a model-ensembling approach to develop an assessment of nocturnal scratch events by measuring scratch duration and intensity. Our assessment is tested in a clinical setting against the ground truth obtained from video recordings. The new approach addresses unmet challenges in existing studies, such as the lack of generalizability to real-world applications, the failure to capture finger scratches, and the limitations in the evaluation due to imbalanced data in the current literature. Furthermore, the performance evaluation shows agreement between derived digital endpoints and the video annotation ground truth, as well as patient-reported outcomes, which demonstrated the validity of the new assessment of nocturnal scratch.

Identifiers

PMID37100893
PMCPMC10133290
OpenAlexW4367055199

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.