Evidence map›Paper›PMID 37100889›Full record

ArticleScientific reports2023

Upregulation of alveolar fluid clearance is not sufficient for Na

Jing Liu, Gillian M Schiralli-Lester, Rosemary Norman, David A Dean

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jing LiuDepartment of Pediatrics, University of Rochester, 601 Elmwood Avenue, Box 850, Rochester, NY, 14642, USA.
Gillian M Schiralli-LesterDepartment of Pediatrics, University of Rochester, 601 Elmwood Avenue, Box 850, Rochester, NY, 14642, USA.
Rosemary NormanDepartment of Pediatrics, University of Rochester, 601 Elmwood Avenue, Box 850, Rochester, NY, 14642, USA.
David A DeanDepartment of Pediatrics, University of Rochester, 601 Elmwood Avenue, Box 850, Rochester, NY, 14642, USA. David_dean@urmc.rochester.edu.
University of Rochester · US

Funding

A multimodal delivery and treatment approach for Acute Lung InjuryR01HL148825 · NHLBI · UNIVERSITY OF ROCHESTER · PI DEAN, DAVID A · 2020 to 2023
$2.3M
NHLBI NIH HHS R01 HL148825
6 · The paper itself

Abstract

Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) is characterized by diffuse alveolar damage and significant edema accumulation, which is associated with impaired alveolar fluid clearance (AFC) and alveolar-capillary barrier disruption, leading to acute respiratory failure. Our previous data showed that electroporation-mediated gene delivery of the Na

Indexed as

Acute Lung InjuryRespiratory Distress SyndromeAnimalsGenetic TherapyLipopolysaccharidesLungMicePulmonary AlveoliSodium-Potassium-Exchanging ATPaseTight Junction ProteinsUp-RegulationLipopolysaccharidesSodium-Potassium-Exchanging ATPaseTight Junction Proteins

Identifiers

PMID37100889
PMCPMC10130817
OpenAlexW4367051583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.