ArticleNature communications2023
Modulation of antibiotic effects on microbial communities by resource competition.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Modelling the role of the microbiome in antimicrobial resistance across scales.Nature microbiology · 2026Review
- Antibiotic-induced gut microbiome dysbiosis: risks and strategies for mitigation.The EMBO journal · 2026Review
- The network structure of cross-feeding impacts microbial community diversity under growth-inhibiting stresses.Nature communications · 2026Article
- The Role of the Environmental Microbiome in Modulating the Spread of Antimicrobial Resistance.Current microbiology · 2026Review
- Microbial interactions in facilitating antibiotic activity and resistance evolution.Applied and environmental microbiology · 2026Review
- Functional redundancy as a stabilizing principle in bacterial communities under antibiotic perturbation: mechanisms, trade-offs, and emerging frameworks.Frontiers in medicine · 2026Review
- Colored Plastic Pollution Reshapes Aquatic Microbial Community and Resistance Profile via Divergent Pseudonatural Dissolved Organic Matter.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Coexistence rules for small, antagonistically interacting microbial communities.PLoS computational biology · 2025Article
- Article
- Gaming the cancer-immunity cycle by synchronizing the dose schedules.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Dynamic coexistence driven by physiological transitions in microbial communities.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Carbon starvation raises capacities in bacterial antibiotic resistance and viral auxiliary carbon metabolism in soils.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Revealing antibiotic resistance's ancient roots: insights from pristine ecosystems.Frontiers in microbiology · 2024Review
- Prolonged delays in human microbiota transmission after a controlled antibiotic perturbation.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Antibiotic treatment significantly impacts the human gut microbiota, but quantitative understanding of how antibiotics affect community diversity is lacking. Here, we build on classical ecological models of resource competition to investigate community responses to species-specific death rates, as induced by antibiotic activity or other growth-inhibiting factors such as bacteriophages. Our analyses highlight the complex dependence of species coexistence that can arise from the interplay of resource competition and antibiotic activity, independent of other biological mechanisms. In particular, we identify resource competition structures that cause richness to depend on the order of sequential application of antibiotics (non-transitivity), and the emergence of synergistic and antagonistic effects under simultaneous application of multiple antibiotics (non-additivity). These complex behaviors can be prevalent, especially when generalist consumers are targeted. Communities can be prone to either synergism or antagonism, but typically not both, and antagonism is more common. Furthermore, we identify a striking overlap in competition structures that lead to non-transitivity during antibiotic sequences and those that lead to non-additivity during antibiotic combination. In sum, our results establish a broadly applicable framework for predicting microbial community dynamics under deleterious perturbations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.