Evidence map›Paper›PMID 37099782›Full record

ArticlePancreas

The Impact of Preexisting Psychiatric Disorders on Outcomes After Pancreatic Cancer Surgery.

Lauren M Perry, Kara T Kleber, Ganesh Rajasekar, Miriam Nuño, Richard J Bold

Open access · greenAbstract read
In one paragraph

Article in Pancreas. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lauren M PerryFrom the Division of Surgical Oncology, Department of Surgery.
Kara T KleberFrom the Division of Surgical Oncology, Department of Surgery.
Ganesh RajasekarDivision of Biostatistics, Department of Public Health Sciences, University of California Davis, Sacramento, CA.
Miriam NuñoDivision of Biostatistics, Department of Public Health Sciences, University of California Davis, Sacramento, CA.
Richard J BoldFrom the Division of Surgical Oncology, Department of Surgery.
University of California, Davis · US

Funding

UC Davis Comparative Oncology Training ProgramT32CA251007 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Robert J. Canter, Xinbin Chen · 2020 to 2026
$1.8M
NCI NIH HHS T32 CA251007
6 · The paper itself

Abstract

objectivesComorbid psychiatric illness has been associated with worse outcomes after some major surgical procedures. We hypothesized that patients with preexisting mood disorders would have worse postoperative and oncologic outcomes after pancreatic cancer resection.

methodsThis retrospective cohort study analyzed Surveillance, Epidemiology, and End Results patients with resectable pancreatic adenocarcinoma. A preexisting mood disorder was classified if a patient was diagnosed and/or treated with medication approved for depression/anxiety within 6 months before surgery.

resultsOf 1305 patients, 16% had a preexisting mood disorder. Mood disorders had no impact on hospital length of stay (12.9 vs 13.2 days, P = 0.75), 30-day complications (26% vs 22%, P = 0.31), 30-day readmissions (26% vs 21%, P = 0.1), or mortality (30 days: 3% vs 4%, P = 0.35); only an increased 90-day readmissions rate (42% vs 31%, P = 0.001) was observed. No effect on adjuvant chemotherapy receipt (62.5% vs 69.2%, P = 0.06) or survival (24 months, 43% vs 39%, P = 0.44) was observed.

conclusionsPreexisting mood disorders influenced 90-day readmissions after pancreatic resection, but not other postoperative or oncologic outcomes. These findings suggest that affected patients should be expected to have outcomes similar to patients without mood disorders.

Indexed as

AdenocarcinomaMental DisordersPancreatic NeoplasmsHumansRetrospective Studies

Identifiers

PMID37099782
PMCPMC10154037
OpenAlexW4367148688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.