Evidence map›Paper›PMID 37099726›Full record

ReviewGlobal spine journal2024

Relative Efficacy of Cervical Total Disc Arthroplasty Devices and Anterior Cervical Discectomy and Fusion for Cervical Pathology: A Network Meta-Analysis.

Athan G Zavras, Vincent P Federico, Alexander J Butler, Michael T Nolte, Navya Dandu, Frank M Phillips, Matthew W Colman

Open access · goldAbstract readReview
In one paragraph

Review in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Athan G ZavrasDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.ORCID 0000-0001-9969-5815
Vincent P FedericoDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.ORCID 0000-0003-3749-9282
Alexander J ButlerDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Michael T NolteDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.ORCID 0000-0001-9293-270X
Navya DanduDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Frank M PhillipsDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Matthew W ColmanDepartment of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Rush University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSystematic Review and Meta Analysis.

objectiveThis study sought to compare patient-reported outcomes, success, complications, and radiographic outcomes directly and indirectly between different cervical total disc arthroplasty (TDA) devices and anterior cervical discectomy and fusion (ACDF).

methodsPatients of prospective randomized controlled trials of 1-level cervical TDA with a minimum of 2 years follow up were identified in the literature. A frequentist network meta-analysis model was used to compare each outcome across the different TDA devices included and ACDF using the mixed effect sizes.

results15 studies were included for quantitative analysis, reporting the outcomes of 2643 patients with an average follow-up was 67.3 months (range: 24-120 months), 1417 of whom underwent TDA and 1226 of whom underwent ACDF. Nine TDA devices were compared to ACDF, including the Bryan, Discover, Kineflex, M6, Mobi-C, PCM, Prestige ST, ProDisc-C, and Secure-C cervical prostheses. Several devices outperformed ACDF for certain outcomes, including Visual Analog Scale (VAS) Arm, Physical Component Score of the Short-Form Health Survey (SF PCS), neurological success, satisfaction, index-level secondary surgical interventions (SSI), and adjacent level surgeries. Cumulative ranking of each intervention assessed demonstrated the highest performance with the M6 prosthesis (

conclusionCervical TDA was found to be superior on most outcomes assessed in the literature of high-quality clinical trials. While most devices demonstrated similar outcomes, certain prostheses such as the M6 were found to outperform others across several outcomes assessed. These findings suggest that the restoration of near-normal cervical kinematics may lead to improved outcomes.

Indexed as

cervicaldegenerative disc diseasedisc herniationdisc replacement

Identifiers

PMID37099726
PMCPMC10676167
OpenAlexW4367041730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.