ArticleScience robotics2023
Bioinspired, ingestible electroceutical capsules for hunger-regulating hormone modulation.
Article in Science robotics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Toward autonomous robotic-assisted and microrobotic surgery.Science advances · 2026Review
- Transforming healthcare through in-body bioelectronic systems.Nature communications · 2026Review
- Edible and Recyclable Gelatin-Based Electronics for High-Precision Health and Environmental Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ethical, legal, and social issues related to ingestible, implantable electronic devices and mRNA delivery devices.Device · 2025Article
- An interoceptive model of energy allostasis linking metabolic and mental health.Science advances · 2025Review
- Ingestible optoelectronic capsules enable bidirectional communication with engineered microbes for controllable therapeutic interventions.Nature microbiology · 2025Article
- Biomimetic Robotics and Sensing for Healthcare Applications and Rehabilitation: A Systematic Review.Biomimetics (Basel, Switzerland) · 2025Review
- An in vitro neurobacterial interface reveals direct modulation of neuronal function by gut bacteria.Scientific reports · 2025Article
- Liquid-based encapsulation for implantable bioelectronics across broad pH environments.Nature communications · 2025Article
- Recent Progress of Soft and Bioactive Materials in Flexible Bioelectronics.Cyborg and bionic systems (Washington, D.C.) · 2025Review
- A Low-Friction Capsule Robot with Drive-Control-Sensing Integration for Gastrointestinal Lesion Detection.Research (Washington, D.C.) · 2025Article
- Smart control lipid-based nanocarriers for fine-tuning gut hormone secretion.Science advances · 2024Article
- Omnidirectional Wireless Power Transfer for Millimetric Magnetoelectric Biomedical Implants.IEEE journal of solid-state circuits · 2024Article
- Gut hormone stimulation as a therapeutic approach in oral peptide delivery.Journal of controlled release : official journal of the Controlled Release Society · 2024Article
- An ingestible, battery-free, tissue-adhering robotic interface for non-invasive and chronic electrostimulation of the gut.Nature communications · 2024Article
- Robotic wireless capsule endoscopy: recent advances and upcoming technologies.Nature communications · 2024Review
- Magnetically driven capsules with multimodal response and multifunctionality for biomedical applications.Nature communications · 2024Article
- Review article: Current status and future directions of ingestible electronic devices in gastroenterology.Alimentary pharmacology & therapeutics · 2024Review
- Battery-free, wireless, and electricity-driven soft swimmer for water quality and virus monitoring.Science advances · 2024Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
The gut-brain axis, which is mediated via enteric and central neurohormonal signaling, is known to regulate a broad set of physiological functions from feeding to emotional behavior. Various pharmaceuticals and surgical interventions, such as motility agents and bariatric surgery, are used to modulate this axis. Such approaches, however, are associated with off-target effects or post-procedure recovery time and expose patients to substantial risks. Electrical stimulation has also been used to attempt to modulate the gut-brain axis with greater spatial and temporal resolution. Electrical stimulation of the gastrointestinal (GI) tract, however, has generally required invasive intervention for electrode placement on serosal tissue. Stimulating mucosal tissue remains challenging because of the presence of gastric and intestinal fluid, which can influence the effectiveness of local luminal stimulation. Here, we report the development of a bioinspired ingestible fluid-wicking capsule for active stimulation and hormone modulation (FLASH) capable of rapidly wicking fluid and locally stimulating mucosal tissue, resulting in systemic modulation of an orexigenic GI hormone. Drawing inspiration from
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.