Evidence map›Paper›PMID 37099438›Full record

ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2023

Skull-vibration-induced nystagmus test in patients who are candidates for intratympanic gentamicin injection.

Giacomo Ciacca, Alfredo Di Giovanni, Luigi Califano, Vito Enrico Pettorossi, Giampietro Ricci, Chiara Pelliccia, Mario Faralli

Open access · goldAbstract read
In one paragraph

Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giacomo CiaccaDepartment of Medicine and Surgery, Otorhinolaryngology Section, University of Perugia, Perugia, Italy.
Alfredo Di GiovanniDepartment of Medicine and Surgery, Otorhinolaryngology Section, University of Perugia, Perugia, Italy.
Luigi CalifanoDepartment of Audiology and Phoniatrics, San Pio Hospital, Benevento, Italy.
Vito Enrico PettorossiDepartment of Medicine and Surgery, Human Physiology and Biochemistry Section, University of Perugia, Perugia, Italy.
Giampietro RicciDepartment of Medicine and Surgery, Otorhinolaryngology Section, University of Perugia, Perugia, Italy.
Chiara PellicciaDepartment of Medicine and Surgery, Human Physiology and Biochemistry Section, University of Perugia, Perugia, Italy.
Mario FaralliDepartment of Medicine and Surgery, Otorhinolaryngology Section, University of Perugia, Perugia, Italy.
University of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to evaluate the utility of the skull-vibration-induced nystagmus test (SVINT) in the selection of patients with Ménière's disease (MD) for intratympanic injection of gentamicin. To date the indications for this treatment have been based only on subjective elements. Methods: A retrospective study was performed in 20 patients diagnosed with unilateral MD. SVINT were performed monthly and the evoked responses were evaluated. After 6 months, the results from patients who were candidates for gentamicin treatment (G group) were compared with those who did not need it (nG group). Correlation with Dizziness Handicap Inventory (DHI) score was evaluated. Results: 120 tests were performed. Positive SVINTs were identified in 52 cases (43.3%) and included excitatory nystagmus in 18 (34.7%), inhibitory nystagmus in 28 (53.8%), and atypical pattern in 6 cases (11.5%). A significant increase excitatory nystagmus was recorded in group G (p = 0.00001). Moreover, there was a significant increase in the DHI score in group G compared with the nG group (p < 0.0001) and in patients with evoked excitatory nystagmus. Conclusions: The finding of excitatory nystagmus during SVINTs performed on several occasions in the follow-up prior to intratympanic injection of gentamicin strengthens this therapeutic choice.

Indexed as

GentamicinsNystagmus, PathologicAnti-Bacterial AgentsHumansInjection, IntratympanicRetrospective StudiesSkullTreatment OutcomeVibrationAnti-Bacterial AgentsGentamicinsintratympanic gentamicin injectionMénière’s diseasenystagmusskull-vibration-induced nystagmus testvestibular system

Identifiers

PMID37099438
PMCPMC10132480
OpenAlexW4367048103

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.