Evidence map›Paper›PMID 37099254›Full record

ReviewJournal of muscle research and cell motility2023

John Squire and the myosin thick filament structure in muscle.

Kenneth A Taylor

Open access · greenAbstract readReview
In one paragraph

Review in Journal of muscle research and cell motility, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Kenneth A TaylorInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL, 32306-4380, USA. ktaylor@fsu.edu.
Florida State University · US

Funding

EM STUDIES ON MUSCLER01GM030598 · NIGMS · FLORIDA STATE UNIVERSITY · PI TAYLOR, KENNETH ALLEN · 1985 to 2020
$4.9M
cryoEM Studies on MuscleR35GM139616 · NIGMS · FLORIDA STATE UNIVERSITY · PI KENNETH ALLEN TAYLOR · 2021 to 2026
$2.9M
NIGMS NIH HHS R01 GM030598NIGMS NIH HHS R35 GM139616
6 · The paper itself

Abstract

The structure of the thin, actin-containing filament of muscle is both highly conserved across a broad range of muscle types and is now well understood. The structure of the thick, myosin-containing filaments of striated muscle are quite variable and remained comparatively unknown until recently, particularly in the arrangement of the myosin tails. John Squire played a major role not only in our understanding of thin filament structure and function but also in the structure of the thick filaments. Long before much was known about the structure and composition of muscle thick filaments, he proposed a general model for how myosin filaments were constructed. His role in our current understanding the structure of striated muscle thick filaments and the extent through which his predictions have held true is the topic of this review.

Indexed as

MyosinsSarcomeresActin CytoskeletonMuscle, SkeletalMyosinsElectron microscopyModelingStriated muscleX-ray fiber diffraction

Identifiers

PMID37099254
PMCPMC10686309
OpenAlexW4367047617

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.