Evidence map›Paper›PMID 37099165›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2023

A delve into the pharmacological targets and biological mechanisms of Paederia foetida Linn.: a rather invaluable traditional medicinal plant.

Mrinal Kashyap Sarma, Dipankar Saha, Bhrigu Kumar Das, Trishna Das, Shavkatjon Azizov, Deepak Kumar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Anxiolytic Effects ofFoods (Basel, Switzerland) · 2025
    Article
  5. Combinatorial chemistry & high throughput screening · 2025
    Review
  6. Article
  7. In Vitro Biological Activities ofInternational journal of molecular sciences · 2024
    Article
  8. Article
  9. Unveiling the pharmacological potential ofFood science & nutrition · 2024
    Article
  10. Therapeutic Potential of the GenusSouth African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mrinal Kashyap SarmaDepartment of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Assam Science and Technology University, Guwahati, 781 017, Assam, India.
Dipankar SahaDepartment of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Assam Science and Technology University, Guwahati, 781 017, Assam, India. drdsaha@gips-guwahati.ac.in.
Bhrigu Kumar DasDepartment of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Assam Science and Technology University, Guwahati, 781 017, Assam, India.
Trishna DasDepartment of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Assam Science and Technology University, Guwahati, 781 017, Assam, India.
Shavkatjon AzizovLaboratory of Biological Active Macromolecular Systems, Institute of Bioorganic Chemistry, Uzbekistan Academy of Sciences, 100125, Tashkent, Uzbekistan.
Deepak KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, 173229, India. guptadeepak002@gmail.com.
Academy of Sciences Republic of Uzbekistan · UZShoolini University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug development from herbal medicines or botanical sources is believed to have a prominent role in the exploration of novel counteractive drugs that has sparked much interest in recent times. Paederia foetida is one such medicinal plant used in both traditional and folkloric medicine. Several parts of the herb are locally utilised as a natural curative agent for several ailments since time immemorial. Paederia foetida indeed possesses anti-diabetic, anti-hyperlipidaemic, antioxidant, nephro-protective, anti-inflammatory, antinociceptive, antitussive, thrombolytic, anti-diarrhoeal, sedative-anxiolytic, anti-ulcer, hepatoprotective activity, anthelmintic and anti-diarrhoeal activity. Furthermore, growing evidence shows many of its active constituents to be effective in cancer, inflammatory diseases, wound healing and spermatogenesis as well. These investigations shed light on possible pharmacological targets and attempts to establish a mechanism of action for these pharmacological effects. These findings contrast the significance of this medicinal plant for further research and for the exploration of novel counteractive drugs to establish a mechanism of action before being employed to healthcare. Pharmacological activities of Paederia foetida and their mechanism of action.

Indexed as

Plants, MedicinalRubiaceaeAnti-Inflammatory AgentsAntioxidantsPhytochemicalsPhytotherapyPlant ExtractsAnti-Inflammatory AgentsAntioxidantsPhytochemicalsPlant ExtractsBiological mechanismMedicinal plantPaederia foetidaPharmacological targets

Identifiers

PMID37099165
OpenAlexW4367041523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.