SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2023
Radiographic OA, bone marrow lesions, higher body mass index and medial meniscal root tears are significantly associated with medial meniscus extrusion with OA or medial meniscal tears: a systematic review and meta-analysis.
Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Subchondral bone remodeling patterns in larger animal models of meniscal injuries inducing knee osteoarthritis - a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Pooled it
- Medial Meniscal Extrusion Increased on 6-Month Magnetic Resonance Imaging, Despite Successful Posterior Root Repair With or Without a Centralization Suture: A Randomized Controlled Clinical Trial.The American journal of sports medicine · 2025Trial
- Female Sex, Higher Outerbridge Grade, and Preoperative Tibial Edema Are Associated With Failure After Arthroscopic Posterior Medial Meniscus Root Repair.Arthroscopy, sports medicine, and rehabilitation · 2026Article
- Relationship between medial meniscus extrusion and osteophyte formation in early-stage knee osteoarthritis: an ultrasound-based multicenter cross-sectional study.Journal of medical ultrasonics (2001) · 2026Article
- Meniscal Extrusion: A Key Modifiable Driver of Meniscal and Cartilage Degeneration.Current reviews in musculoskeletal medicine · 2026Review
- Gait and plantar pressure changes after medial open-wedge high tibial osteotomy combined with arthroscopic partial meniscectomy.Frontiers in bioengineering and biotechnology · 2026Article
- Transtibial repair of medial meniscus posterior root tears: Interference screw fixation improves primary stability in a porcine model.Journal of experimental orthopaedics · 2025Article
- A systematic review and meta-analysis examining alterations in medial meniscus extrusion and clinical outcomes following high tibial osteotomy.Journal of orthopaedics · 2025Review
- Ultrasound quantification of knee meniscal extrusion: the potential of weight-bearing and dynamic evaluations. A systematic review.EFORT open reviews · 2025Article
- Occupational motions such as kneeling and squatting are associated with the increased development of medial meniscus posterior root tears, regardless of the medial posterior tibial slope angle.Journal of experimental orthopaedics · 2025Article
- Changes in the position of the medial meniscus owing to degenerative meniscus tears.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2025Article
- Meniscal extrusion: Proposal for a novel qualitative classification.Journal of experimental orthopaedics · 2025Review
- Association between meniscal extrusion and disease severity in knee osteoarthritis: a retrospective case-control study.BMC musculoskeletal disorders · 2024Article
- Diagnosis and Treatment Strategies of Meniscus Root Tears: A Scoping Review.Orthopaedic journal of sports medicine · 2024Article
- Arthroscopic Belt Capsulodesis Using a Knotless Soft Suture Anchor for Extruded Medial Meniscus.Arthroscopy techniques · 2024Article
- Favorable early outcomes of medial unicompartimental knee arthroplasty in active patients presenting a degenerative medial meniscus root tear with meniscal extrusion and mild radiographic osteoarthritis.Archives of orthopaedic and trauma surgery · 2024Article
- Insufficient restoration of meniscal extrusion by transtibial pullout repair for medial meniscus posterior root tears.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
purposeMedial meniscus extrusion (MME) refers to the protrusion of the medial meniscus beyond the tibial edge by more than 3 mm, leading to a deficiency of the hoop strain. MME commonly occurs in conjunction with osteoarthritis (OA) or medial meniscal tears (MMT). However, factors associated with concomitant MME in patients with OA or MMT have not been systematically reviewed. This study aims to perform a systematic review and meta-analysis to identify factors associated with concomitant MME in OA or MMT.
methodsThe systematic review of the literature was performed according to PRISMA. A literature search was conducted in 4 databases. All original human studies that reported the available evidence on factors associated with concomitant MME in patients with OA or MMT were included. Pooled binary variables were analyzed by odds ratios (OR) and 95% CIs, and pooled continuous variables were evaluated by mean difference (MD) and 95% CIs.
resultsTen studies on OA (5993 patients) and eight studies on MMT (872 patients) met the inclusion criteria. The overall pooled incidence of MME was 43% (95% CI, 37-50%) for OA, 61% (95% CI 43-77%) for MMT, and 85% (95% CI 72-94%) for medial meniscal root tears (MMRT). For the population with OA, Factors significantly associated with MME included radiographic OA [OR 4.24; 95% CI 3.07-5.84; P < 0.0001], bone marrow lesions [OR, 3.35; 95% CI 1.61-6.99; P = 0.0013], cartilage damage [OR, 3.25; 95% CI 1.60-6.61; P = 0.0011], and higher body mass index (BMI) [MD, 1.81; 95% CI 1.15-2.48; P < 0.0001]. Factors strongly associated with increased risk of MME for MMT included medial meniscal root [OR, 8.39; 95% CI 2.84-24.82; P < 0.0001] and radial tears [OR, 2.64; 95% CI 1.18-5.92; P < 0.0001].
conclusionRadiographic OA, bone marrow lesions, cartilage damage, and higher BMI were significantly associated with concomitant MME with OA. Furthermore, medial meniscal root and radial tears were significantly associated with an increased risk of MME in patients with MMT. LEVEL OF EVIDENCE: IV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.