Evidence map›Paper›PMID 37098979›Full record

ArticleJournal of bacteriology2023

Regulatory Role of Anti-Sigma Factor RsbW in Clostridioides difficile Stress Response, Persistence, and Infection.

Jeffrey K J Cheng, Tanja Đapa, Ivan Y L Chan, Thomas O MacCreath, Ross Slater, Meera Unnikrishnan

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Journal of bacteriology · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jeffrey K J ChengDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0000-0002-4093-7872
Tanja ĐapaInstituto Gulbenkian de Ciência, Oeiras, Portugal.
Ivan Y L ChanDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0009-0005-4149-6289
Thomas O MacCreathDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Ross SlaterDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Meera UnnikrishnanDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.ORCID 0000-0001-5417-9331
University of Warwick · GBInstituto Gulbenkian de Ciência · PT

Funding

UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) 1897785
6 · The paper itself

Abstract

The anaerobic pathogen Clostridioides difficile, which is a primary cause of antibiotic-associated diarrhea, faces a variety of stresses in the environment and in the mammalian gut. To cope with these stresses, alternative sigma factor B (σ

Indexed as

Clostridioides difficileSigma FactorAnimalsBacterial ProteinsClostridioidesComplement Factor BGene Expression Regulation, BacterialHumansMammalsTranscription FactorsBacterial ProteinsComplement Factor BSigma FactorTranscription Factorsanti-sigma factor RsbWClostridioides difficileregulationsigma factor Bstress responses

Identifiers

PMID37098979
PMCPMC10210984
OpenAlexW4367047793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.