ArticleScience signaling2023
MICU1 regulates mitochondrial cristae structure and function independently of the mitochondrial Ca
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Article in Science signaling, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
What it found
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Who cites it
45 citing papers in PubMed, 58 citations in OpenAlex.
- Mechanistic basis of EMRE's essential role in the regulation of mitochondrial calcium uniporter complex.bioRxiv : the preprint server for biology · 2026Article
- MICU proteins facilitate calcium-dependent mitochondrial metabolon formation to regulate cellular energetics independently of MCU.Nature metabolism · 2026Article
- The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney.Aging cell · 2026Article
- The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney.bioRxiv : the preprint server for biology · 2026Article
- Tmbim5 and Slc8b1 cooperate in tissue-specific mitochondrial calcium regulation in zebrafish.Communications biology · 2026Article
- Eicosanoid-immunometabotypes reveal genotypic links to cervicovaginal pH in progestagen synchronised South African Dohne Merino ewes.Frontiers in veterinary science · 2026Article
- Increased Intermembrane Space [CaCirculation research · 2025Article
- Cell-type-specific dysregulation of mitochondrial calcium signaling in Alzheimer's disease.Cell communication and signaling : CCS · 2025Article
- Adaptation to Elevated Mitochondrial Calcium Is Distinct in the Left and Right Ventricles.Circulation research · 2025Article
- Interaction of the mitochondrial calcium/proton exchanger TMBIM5 with MICU1.Communications biology · 2025Article
- Molecular machineries shaping the mitochondrial inner membrane.Nature reviews. Molecular cell biology · 2025Review
- MICU proteins facilitate CaResearch square · 2025Article
- The roles of mitochondria in global and local intracellular calcium signalling.Nature reviews. Molecular cell biology · 2025Review
- Mitochondrial Calcium Uniporter (MCU)-Mediated Calcium Overload in Psychoactive Drug Neurotoxicity: From Pathogenesis to Therapeutic Targets.International journal of molecular sciences · 2025Review
- HRP2 regulating MICU1-mediated CaNeoplasia (New York, N.Y.) · 2025Article
- Compositionally unique mitochondria in filopodia support cellular migration.Current biology : CB · 2025Article
- Article
- Mitochondrial membrane synthesis, remodelling and cellular trafficking.Journal of inherited metabolic disease · 2025Review
- Systematic mapping of mitochondrial calcium uniporter channel (MCUC)-mediated calcium signaling networks.The EMBO journal · 2024Article
- Calcium signaling in mitochondrial intermembrane space.Biochemical Society transactions · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Dhanendra TomarCardiovascular Research Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0002-3144-7257
Manfred ThomasCardiovascular Research Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.
Joanne F GarbinciusCardiovascular Research Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0002-4334-6445
Devin W KolmetzkyCardiovascular Research Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0001-8905-0079
Oniel SalikCardiovascular Research Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0001-9785-4173
Pooja JadiyaCardiovascular Research Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.
Suresh K JosephMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
April C CarpenterHealth and Exercise Physiology, Ursinus College, Collegeville, PA 19426, USA.ORCID 0000-0002-6987-6612
György HajnóczkyMitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.ORCID 0000-0003-3813-2570
John W ElrodCardiovascular Research Center, Department of Cardiovascular Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.ORCID 0000-0003-3925-2224
Temple University · USThomas Jefferson University · USUrsinus College · US
Funding
Small and large animal surgery, physiology and histologyP01HL134608 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI Walter J. Koch · 2017 to 2026
$21.0MTargeting Pathways Involved in Cardiac Injury for Novel Repair StrategiesP01HL147841 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2020 to 2024
$11.4MIntegrative Cardiovascular PathophysiologyT32HL091804 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2008 to 2024
$4.5MMolecular composition of the mitochondrial calcium uniporter and cardiac pathophysiologyR01HL142271 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI ELROD, JOHN WILLIAM, HAJNOCZKY, GYORGY · 2018 to 2021
$3.0MMechanisms of mitochondrial calcium exchange in heart failureR01HL123966 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2014 to 2018
$2.3MMitochondria and metabolism in neurodegenerationRF1NS121379 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2021 to 2021
$2.3MNovel Molecular Mechanisms of Programmed NecrosisR01HL136954 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2017 to 2020
$1.6MRegulation of inositol trisphosphate receptorsR01GM132611 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI JOSEPH, SURESH K · 2020 to 2023
$1.3MImpact of mitochondrial structure on cellular homeostasis and hepatic injuryR00DK120876 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI TOMAR, DHANENDRA · 2022 to 2024
$986kMitochondrial calcium uptake in Alzheimer's disease. Admin SupplementR00AG065445 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI JADIYA, POOJA · 2022 to 2024
$845kMitochondrial calcium uptake in Alzheimer's diseaseK99AG065445 · NIA · TEMPLE UNIV OF THE COMMONWEALTH · PI JADIYA, POOJA · 2020 to 2021
$208kImpact of mitochondrial structure on cellular homeostasis and hepatic injuryK99DK120876 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI TOMAR, DHANENDRA · 2020 to 2021
$181kAmerican Heart Association-American Stroke Association 17POST33660251NHLBI NIH HHS F32 HL151146NHLBI NIH HHS P01 HL134608NHLBI NIH HHS P01 HL147841NHLBI NIH HHS R01 HL123966NHLBI NIH HHS R01 HL136954NHLBI NIH HHS R01 HL142271NHLBI NIH HHS T32 HL091804NIA NIH HHS K99 AG065445NIA NIH HHS R00 AG065445NIDDK NIH HHS K99 DK120876NIDDK NIH HHS R00 DK120876NIGMS NIH HHS R01 GM132611NINDS NIH HHS RF1 NS121379
Abstract
MICU1 is a calcium (Ca
Indexed as
Mitochondrial MembranesProteomicsAnimalsCalciumCalcium-Binding ProteinsCalcium ChannelsMiceMice, KnockoutMitochondriaMitochondrial Membrane Transport ProteinsMitochondrial ProteinsCalciumCalcium-Binding ProteinsCalcium ChannelsMICU1 protein, mouseMitochondrial Membrane Transport ProteinsMitochondrial Proteins
Identifiers
What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.