Evidence map›Paper›PMID 37098069›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Programmed cell death-1 receptor-mediated regulation of Tbet

Jing Xuan Lim, Chester Y Lai, Grace E Mallett, David McDonald, Gillian Hulme, Stephanie Laba, Andrew Shapanis, Megan Payne, Warren Patterson, Michael Alexander and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Innate Immune Cells in Melanoma: Implications for Immunotherapy.International journal of molecular sciences · 2024
    Review
  8. Review
  9. Programmed cell death-1 receptor-mediated regulation of TbetProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Jing Xuan LimNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Chester Y LaiDermatopharmacology, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, United Kingdom.
Grace E MallettNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
David McDonaldNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Gillian HulmeNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Stephanie LabaNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Andrew ShapanisDermatopharmacology, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, United Kingdom.
Megan PayneNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Warren PattersonNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Michael AlexanderNewcastle University Centre for Cancer, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Jonathan CoxheadNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Andrew FilbyNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Ruth PlummerNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Penny E LovatNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Giuseppe SciumeDepartment of Molecular Medicine, Sapienza University of Rome Laboratory affiliation to Institute Pasteur Italia-Fondazione Cenci Bolognetti, Rome 00161, Italy.
Eugene HealyDermatopharmacology, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, United Kingdom.
Shoba AmarnathNewcastle University Biosciences Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Newcastle University · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Newcastle Australia · AUSapienza University of Rome · ITUniversity of Southampton · GB

Funding

Medical Research Council 1953078Medical Research Council MR/T015586/1Medical Research Council MR/W03039X/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/W002043/1Wellcome Trust SBF003/1129
6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) play a key role in tissue-mediated immunity and can be controlled by coreceptor signaling. Here, we define a subset of ILCs that are Tbet

Indexed as

LymphocytesNeoplasmsAnimalsApoptosisHumansImmunity, InnateMammalsMiceProgrammed Cell Death 1 ReceptorTumor MicroenvironmentProgrammed Cell Death 1 ReceptorcSCCILCmelanomaPD-1

Identifiers

PMID37098069
PMCPMC10161089
OpenAlexW4366981302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.