Evidence map›Paper›PMID 37098062›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Conservation management strategy impacts inbreeding and mutation load in scimitar-horned oryx.

Emily Humble, Martin A Stoffel, Kara Dicks, Alex D Ball, Rebecca M Gooley, Justin Chuven, Ricardo Pusey, Mohammed Al Remeithi, Klaus-Peter Koepfli, Budhan Pukazhenthi and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  17. Natural dispersal is better than translocation for reducing risks of inbreeding depression in eastern black rhinoceros (Proceedings of the National Academy of Sciences of the United States of America · 2025
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  18. Article
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  20. Runs of Homozygosity Preliminary Investigation in Pig Breeds.Animals : an open access journal from MDPI · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Emily HumbleRoyal (Dick) School of Veterinary Studies and the Roslin Institute, University of Edinburgh, Edinburgh EH25 9RG, United Kingdom.ORCID 0000-0001-6841-1269
Martin A StoffelInstitute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.ORCID 0000-0003-4030-3543
Kara DicksRZSS WildGenes, Conservation Department, Royal Zoological Society of Scotland, Edinburgh EH12 6TS, United Kingdom.ORCID 0000-0002-3764-4315
Alex D BallRZSS WildGenes, Conservation Department, Royal Zoological Society of Scotland, Edinburgh EH12 6TS, United Kingdom.
Rebecca M GooleySmithsonian-Mason School of Conservation, George Mason University, Front Royal, VA 22630.
Justin ChuvenTerrestrial & Marine Biodiversity Sector, Environment Agency - Abu Dhabi, United Arab Emirates.
Ricardo PuseyTerrestrial & Marine Biodiversity Sector, Environment Agency - Abu Dhabi, United Arab Emirates.
Mohammed Al RemeithiTerrestrial & Marine Biodiversity Sector, Environment Agency - Abu Dhabi, United Arab Emirates.
Klaus-Peter KoepfliSmithsonian-Mason School of Conservation, George Mason University, Front Royal, VA 22630.ORCID 0000-0001-7281-0676
Budhan PukazhenthiSmithsonian's National Zoo and Conservation Biology Institute, Center for Species Survival, Front Royal, VA 22630 and Washington, DC 20008.
Helen SennRZSS WildGenes, Conservation Department, Royal Zoological Society of Scotland, Edinburgh EH12 6TS, United Kingdom.
Rob OgdenRoyal (Dick) School of Veterinary Studies and the Roslin Institute, University of Edinburgh, Edinburgh EH25 9RG, United Kingdom.ORCID 0000-0002-2831-0428
Royal Zoological Society of Scotland · GBEnvironment Agency Abu Dhabi · AEGeorge Mason University · USRoslin Institute · GBSmithsonian Conservation Biology Institute · USUnited States Fish and Wildlife Service · USUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an age of habitat loss and overexploitation, small populations, both captive and wild, are increasingly facing the effects of isolation and inbreeding. Genetic management has therefore become a vital tool for ensuring population viability. However, little is known about how the type and intensity of intervention shape the genomic landscape of inbreeding and mutation load. We address this using whole-genome sequence data of the scimitar-horned oryx (

Indexed as

AntelopesInbreedingAllelesAnimalsGenotypeHomozygoteMutationPolymorphism, Single Nucleotidedeleterious mutationseffective population sizeex situ populationsreintroductionruns of homozygosity (ROH)

Identifiers

PMID37098062
PMCPMC10160979
OpenAlexW4366981281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.