ReviewExpert review of anti-infective therapy2023
New insights into the treatment of acute otitis media.
Review in Expert review of anti-infective therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 33 citations in OpenAlex.
- Diagnostic accuracy and management of suspected acute otitis media: A multi-continental survey of primary care physicians using tympanic membrane images in clinical cases.The European journal of general practice · 2026Article
- Incidence of mastoiditis complications in relation to prior community-based antibiotic treatment.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- The Gut-Ear Axis: From Dysbiosis to Auditory and Vestibular Disorders.International journal of molecular sciences · 2026Review
- Telehealth Approaches for Pediatric Otitis Media and Clinical Outcomes: Scoping Review.Journal of medical Internet research · 2026Article
- Terpene-augmented novasomal carriers for trans-tympanic drug delivery: a comprehensive optimization and in vivo evaluation.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Transcutaneous auricular vagus nerve stimulation promotes recovery from otitis media by activating the α7nAChR-mediated anti-inflammatory pathway.Inflammation and regeneration · 2026Article
- Cost to implement an outpatient stewardship intervention for acute otitis media (AOM).Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Systems perspectives on pediatric otitis media: environmental exposures, genetic susceptibility, and biomarker-guided interventions.Frontiers in pediatrics · 2026Review
- Systematic analysis of global trends in otitis media burden across Socio-Demographic Index levels, 1990-2021: findings from the global burden of disease study 2021.Frontiers in public health · 2026Article
- Paediatric Otorhinolaryngological Disorders: Early Detection and Management Strategies.Cureus · 2025Article
- Emergencies in Otorhinolaryngology: Diagnostic Evaluation, Assessment of Urgency, and Treatment.Deutsches Arzteblatt international · 2025Review
- Utilizing temporal imaging to enhance early diagnosis of eosinophilic otitis media in clinical practice.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- The Diagnosis, Management, and Outcomes of Gradenigo Syndrome in Children: A Scoping Review of the Literature.Diagnostics (Basel, Switzerland) · 2025Review
- Post-Pandemic Surge in Complications of Acute Otitis Media.Turkish archives of otorhinolaryngology · 2025Article
- Trends in the incidence and burden of otitis media in children: a global analysis from 1990 to 2021.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Surgical Management of a Rare Complication of Mastoidectomy: A Retroauricular Cutaneous-Mastoid Fistula.Cureus · 2025Article
- Probiotic, Prebiotic, and Synbiotic Supplementation for the Prevention and Treatment of Acute Otitis Media: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2025Review
- Effect of Anti-Programmed Cell Death-1 Antibody on Middle Ear Mucosal Immune Response to Intranasal Administration ofVaccines · 2025Article
- Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040.Frontiers in public health · 2025Article
- IgM mediated cefotaxime resistance ofAmerican journal of translational research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
introductionAcute otitis media (AOM) affects most (80%) children by 5 years of age and is the most common reason children are prescribed antibiotics. The epidemiology of AOM has changed considerably since the widespread use of pneumococcal conjugate vaccines, which has broad-reaching implications for management. AREAS COVERED: In this narrative review, we cover the epidemiology of AOM, best practices for diagnosis and management, new diagnostic technology, effective stewardship interventions, and future directions of the field. Literature review was performed using PubMed and ClinicalTrials.gov. EXPERT OPINION: Inaccurate diagnoses, unnecessary antibiotic use, and increasing antimicrobial resistance remain major challenges in AOM management. Fortunately, effective tools and interventions to improve diagnostic accuracy, de-implement unnecessary antibiotic use, and individualize care are on the horizon. Successful scaling of these tools and interventions will be critical to improving overall care for children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.