Evidence map›Paper›PMID 37097176›Full record

ArticleJournal of virology2023

Interplay between Furin and Sialoglycans in Modulating Adeno-Associated Viral Cell Entry.

Timothy J Smith, Robert M Fusco, Zachary C Elmore, Aravind Asokan

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Timothy J SmithDepartment of Molecular Genetics & Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-3285-4698
Robert M FuscoDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Zachary C ElmoreDepartment of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.
Aravind AsokanDepartment of Molecular Genetics & Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0001-5563-4877
Duke University · US

Funding

Determinants of AAV TropismR01HL089221 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Aravind Asokan · 2009 to 2026
$8.1M
Evolving Novel AAV Vectors for Gene Therapy to Cure HIVR01AI166969 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI ASOKAN, ARAVIND, SACHA, JONAH B. · 2022 to 2025
$4.9M
RE-ENGINEERING AAV GENOME PACKAGINGR01GM127708 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ASOKAN, ARAVIND · 2018 to 2021
$2.0M
NHLBI NIH HHS R01 HL089221NIAID NIH HHS R01 AI166969NIGMS NIH HHS R01 GM127708
6 · The paper itself

Abstract

Adeno-associated viruses (AAVs) are small, helper-dependent, single-stranded DNA viruses that exploit a broad spectrum of host factors for cell entry. During the course of infection, several AAV serotypes have been shown to transit through the

Indexed as

DependovirusVirus InternalizationAnimalsCapsid ProteinsChlorocebus aethiopsFurinGenetic VectorsTransduction, GeneticCapsid ProteinsFurinadeno-associated viruscell surfacesialic acidsubcellular localizationvirus-host interactions

Identifiers

PMID37097176
PMCPMC10231208
OpenAlexW4366984156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.