Evidence map›Paper›PMID 37096979›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2023

Catheter ablation of intramural outflow tract premature ventricular complexes: a multicentre study.

Matthew Hanson, Piotr Futyma, Weeranun Bode, Jackson J Liang, Carlos Tapia, Christian Adams, Łukasz Zarębski, Aleksandra Wrzos, Luis Saenz, Mouhannad Sadek and 6 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 37 citations in OpenAlex.

  1. Focal pulsed field ablation for complex ventricular arrhythmias after prior failed or intraprocedurally ineffective radiofrequency ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
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  11. Enhancing origin prediction: deep learning model for diagnosing premature ventricular contractions with dual-rhythm analysis focused on cardiac rotation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  12. Enhancing origin prediction: deep learning model for diagnosing premature ventricular contractions with dual-rhythm analysis focused on cardiac rotation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  13. Enhancing origin prediction: deep learning model for diagnosing premature ventricular contractions with dual-rhythm analysis focused on cardiac rotation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  14. Bipolar radiofrequency ablation of refractory ventricular arrhythmias: results from a multicentre network.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  15. Safety and efficacy of same-day discharge for premature ventricular complex ablations.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  16. Diagnostic reliability of monitoring for premature atrial and ventricular complexes.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  17. Safety and efficacy of same-day discharge for premature ventricular complex ablations.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  18. The catheter anatomical guidance facilitates ethanol ablation of ventricular arrhythmias from the left ventricular summit.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  19. Stereotactic arrhythmia radioablation and its implications for modern cardiac electrophysiology: results of an EHRA survey.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 4 countries.

Matthew HansonDivision of Cardiology, Queen's University, 76 Stuart Street, Kingston, Ontario K7L 2V7, Canada.
Piotr FutymaUniversity of Rzeszów and St. Joseph's Heart Rhythm Center, Rzeszów, Poland.ORCID 0000-0003-0219-7612
Weeranun BodeElectrophysiology Section, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3128-1269
Jackson J LiangDivision of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-8608-8899
Carlos TapiaFundación Cardioinfantil, Instituto de Cardiología, Bogotá, Colombia.
Christian AdamsFundación Cardioinfantil, Instituto de Cardiología, Bogotá, Colombia.ORCID 0000-0002-9538-8583
Łukasz ZarębskiUniversity of Rzeszów and St. Joseph's Heart Rhythm Center, Rzeszów, Poland.ORCID 0000-0003-2524-7950
Aleksandra WrzosUniversity of Rzeszów and St. Joseph's Heart Rhythm Center, Rzeszów, Poland.ORCID 0000-0003-4117-574X
Luis SaenzFundación Cardioinfantil, Instituto de Cardiología, Bogotá, Colombia.ORCID 0000-0002-2693-4720
Mouhannad SadekDivision of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.ORCID 0000-0003-2526-9359
Daniele MuserElectrophysiology Section, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-4323-5988
Adrian BaranchukDivision of Cardiology, Queen's University, 76 Stuart Street, Kingston, Ontario K7L 2V7, Canada.ORCID 0000-0002-3042-6569
Francis MarchlinskiElectrophysiology Section, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7962-9423
Pasquale SantangeliElectrophysiology Section, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-0023-9666
Fermin GarciaElectrophysiology Section, Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Andres EnriquezDivision of Cardiology, Queen's University, 76 Stuart Street, Kingston, Ontario K7L 2V7, Canada.ORCID 0000-0002-8146-360X
Hospital of the University of Pennsylvania · USInstitute of Cardiology · COQueen's University · CAUniversity of Rzeszów · PLUniversity of Michigan · USUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsAblation of outflow tract ventricular arrhythmias may be limited by a deep intramural location of the arrhythmogenic source. This study evaluates the acute and long-term outcomes of patients undergoing ablation of intramural outflow tract premature ventricular complexes (PVCs). METHODS AND

resultsThis multicenter series included patients with structurally normal heart or nonischemic cardiomyopathy and intramural outflow tract PVCs defined by: (a) ≥ 2 of the following criteria: (1) earliest endocardial or epicardial activation < 20ms pre-QRS; (2) Similar activation in different chambers; (3) no/transient PVC suppression with ablation at earliest endocardial/epicardial site; or (b) earliest ventricular activation recorded in a septal coronary vein. Ninety-two patients were included, with a mean PVC burden of 21.5±10.9%. Twenty-six patients had had previous ablations. All PVCs had inferior axis, with LBBB pattern in 68%. In 29 patients (32%) direct mapping of the intramural septum was performed using an insulated wire or multielectrode catheter, and in 13 of these cases the earliest activation was recorded within a septal vein. Most patients required special ablation techniques (one or more), including sequential unipolar ablation in 73%, low-ionic irrigation in 26%, bipolar ablation in 15% and ethanol ablation in 1%. Acute PVC suppression was achieved in 75% of patients. Following the procedure, the PVC burden was reduced to 5.8±8.4%. The mean follow-up was 15±14 months and 16 patients underwent a repeat ablation.

conclusionAblation of intramural PVCs is challenging; acute arrhythmia elimination is achieved in 3/4 patients, and non-conventional approaches are often necessary for success.

Indexed as

Catheter AblationTachycardia, VentricularVentricular Premature ComplexesEndocardiumHeart VentriclesHumansTreatment OutcomeCatheter ablationIntramuralMappingRadiofrequencyVentricular arrhythmias

Identifiers

PMID37096979
PMCPMC10228610
OpenAlexW4366985246

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.