Evidence map›Paper›PMID 37096840›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Engineering Cell Membrane-Cloaked Catalysts as Multifaceted Artificial Peroxisomes for Biomedical Applications.

Dongmei Yang, Yuanjiao Tang, Bihui Zhu, Houqing Pang, Xiao Rong, Yang Gao, Fangxue Du, Chong Cheng, Li Qiu, Lang Ma

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. [Experimental Study on Biomimetic Curcumin-Mediated Sonodynamic Therapy of Melanoma].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dongmei YangDepartment of Ultrasound, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Med-X Center for Materials, Sichuan University, Chengdu, 610041, China.
Yuanjiao TangDepartment of Ultrasound, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Med-X Center for Materials, Sichuan University, Chengdu, 610041, China.
Bihui ZhuDepartment of Ultrasound, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Med-X Center for Materials, Sichuan University, Chengdu, 610041, China.
Houqing PangDepartment of Ultrasound, West China Second University Hospital, Sichuan University, Chengdu, 610041, China.
Xiao RongDepartment of Ultrasound, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Med-X Center for Materials, Sichuan University, Chengdu, 610041, China.
Yang GaoCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu, 610065, China.
Fangxue DuDepartment of Ultrasound, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Med-X Center for Materials, Sichuan University, Chengdu, 610041, China.
Chong ChengCollege of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu, 610065, China.
Li QiuDepartment of Ultrasound, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Med-X Center for Materials, Sichuan University, Chengdu, 610041, China.
Lang MaDepartment of Ultrasound, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Med-X Center for Materials, Sichuan University, Chengdu, 610041, China.ORCID 0000-0003-3741-1885

Funding

1·3·5 Project for Disciplines of Excellence, West China Hospital, Sichuan University ZYJC21047Chengdu Science and Technology Program 2021-YF05-01297-SNChengdu Science and Technology Program 2021-YF05-01661-SNChengdu Science and Technology Project 2021-YF05-01297-SNChengdu Science and Technology Project 2021-YF05-01661-SNChunhui Program of the Ministry of EducationMedical Science and Technology Project of Sichuan Provincial Health Commission 21PJ011Medical Science and Technology Project of Sichuan Provincial Health Commission 21PJ012Med-X Center for Materials, Sichuan University MCM202102National Natural Science Foundation of China 82001829National Natural Science Foundation of China 82071938National Natural Science Foundation of China 82202187National Natural Science Foundation of China 82272003Science and Technology Project of Sichuan Province 2021YFS0050Science and Technology Project of Sichuan Province 2022YFH0111Science and Technology Project of Sichuan Province 2022YFH0112Science and Technology Project of Sichuan Province 2022YFH0113
6 · The paper itself

Abstract

Artificial peroxisomes (APEXs) or peroxisome mimics have caught a lot of attention in nanomedicine and biomaterial science in the last decade, which have great potential in clinically diagnosing and treating diseases. APEXs are typically constructed from a semipermeable membrane that encloses natural enzymes or enzyme-mimetic catalysts to perform peroxisome-/enzyme-mimetic activities. The recent rapid progress regarding their biocatalytic stability, adjustable activity, and surface functionality has significantly promoted APEXs systems in real-life applications. In addition, developing a facile and versatile system that can simulate multiple biocatalytic tasks is advantageous. Here, the recent advances in engineering cell membrane-cloaked catalysts as multifaceted APEXs for diverse biomedical applications are highlighted and commented. First, various catalysts with single or multiple enzyme activities have been introduced as cores of APEXs. Subsequently, the extraction and function of cell membranes that are used as the shell are summarized. After that, the applications of these APEXs are discussed in detail, such as cancer therapy, antioxidant, anti-inflammation, and neuron protection. Finally, the future perspectives and challenges of APEXs are proposed and outlined. This progress review is anticipated to provide new and unique insights into cell membrane-cloaked catalysts and to offer significant new inspiration for designing future artificial organelles.

Indexed as

NanomedicinePeroxisomesBiocompatible MaterialsCatalysisCell MembraneBiocompatible Materialsartificial peroxisomebiomedical applicationcatalystcell membranereactive oxygen species

Identifiers

PMID37096840
PMCPMC10265064

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.