Evidence map›Paper›PMID 37096827›Full record

ArticleCancer2023

Neighborhood attributes and cardiovascular disease risk in breast cancer survivors: The Pathways Study.

Shannon M Conroy, Julie Von Behren, Marilyn L Kwan, Lawrence H Kushi, Mi-Ok Kim, Carlos Iribarren, Janise M Roh, Cecile A Laurent, Catherine Thomsen, Janet N Chu and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Assessing Upstream Structural and Social Drivers of Health in Breast Cancer Survivorship: The Pathways Study Neighborhood Resource.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Shannon M ConroyDepartment of Public Health Sciences, School of Medicine, University of California, Davis, Davis, California, USA.
Julie Von BehrenDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-9342-5299
Marilyn L KwanDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.ORCID 0000-0001-8863-3950
Lawrence H KushiDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Mi-Ok KimDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.
Carlos IribarrenDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Janise M RohDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Cecile A LaurentDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Catherine ThomsenZero Breast Cancer, San Rafael, California, USA.
Janet N ChuDivision of General Internal Medicine, University of California, San Francisco, San Francisco, California, USA.
Heather GreenleePublic Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA.
Scarlett Lin GomezDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-5143-4867
Salma Shariff-MarcoDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-2541-3333
Kaiser Permanente · USUniversity of California, San Francisco · USFred Hutch Cancer Center · USSan Francisco General Hospital · USUniversity of California, Davis · USZero Breast Cancer · US

Funding

Prospective Study of Breast Cancer SurvivorshipR01CA105274 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUSHI, LAWRENCE H · 2004 to 2014
$19.9M
Infrastructure for Pathways, a Prospective Study of Breast Cancer SurvivorshipU01CA195565 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI AMBROSONE, CHRISTINE B., KUSHI, LAWRENCE H · 2016 to 2025
$18.8M
Predictors of CVD among breast cancer survivors in an integrated health systemR01CA214057 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI GREENLEE, HEATHER, KWAN, MARILYN L · 2017 to 2020
$2.6M
Developing CVD prediction models for women with early stage breast cancerU01CA214057 · NCI · FRED HUTCHINSON CANCER CENTER · PI Heather Greenlee · 2025 to 2026
$1.5M
NCI NIH HHS 5R01CA214057NCI NIH HHS R01 CA105274NCI NIH HHS R01 CA214057NCI NIH HHS U01 CA195565NCI NIH HHS U01 CA214057
6 · The paper itself

Abstract

backgroundBreast cancer survivors are at a higher risk of cardiovascular disease (CVD) morbidity and mortality compared with the general population. The impact of objective social and built neighborhood attributes on CVD risk in a cohort of female breast cancer survivors was examined.

methodsThe 3975 participants came from the Pathways Study, a prospective cohort of women with invasive breast cancer from an integrated health care system in northern California. Women diagnosed with breast cancer from 2006 through 2013 were enrolled on average approximately 2 months after diagnosis. Their baseline addresses were geocoded and appended to neighborhood attributes for racial/ethnic composition, socioeconomic status (SES), population density, urbanization, crime, traffic density, street connectivity, parks, recreational facilities, and retail food environment. Incident CVD events included ischemic heart disease, heart failure, cardiomyopathy, or stroke. Cox proportional hazards models estimated associations of neighborhood attributes with CVD risk, which accounted for clustering by block groups. Fully adjusted models included sociodemographic, clinical, and behavioral factors.

resultsDuring follow-up through December 31, 2018, 340 participants (8.6%) had CVD events. A neighborhood racial/ethnic composition measure, percent of Asian American/Pacific Islander residents (lowest quintile hazard ratio [HR], 1.85; 95% CI, 1.03-3.33), and crime index (highest quartile HR, 1.48; 95% CI, 1.08-2.03) were associated with the risk of CVD events independent of individual SES, hormone receptor status, treatment, cardiometabolic comorbidities, body mass index, and physical activity.

conclusionsWith the application of a socio-ecological framework, how residential environments shape health outcomes in women with breast cancer and affect CVD risk in this growing population can be understood.

Indexed as

Breast NeoplasmsCancer SurvivorsCardiovascular DiseasesFemaleHumansProspective StudiesResidence Characteristicsbreast cancer survivorscardiovascular riskcrimeneighborhoodsocial environment

Identifiers

PMID37096827
PMCPMC10506517
OpenAlexW4366986355

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.