Evidence map›Paper›PMID 37096743›Full record

ReviewJournal of investigative medicine high impact case reports

Radiation Recall Dermatitis Following Treatment With Pembrolizumab: A Case Report and Review of the Literature.

Michael Sandhu, Prashanth Ashok Kumar, Jared Deck, Maroun Bou Zerdan, Michael Lacombe, Abirami Sivapiragasam

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michael SandhuSUNY Upstate Medical University, Syracuse, USA.ORCID 0000-0001-6200-5083
Prashanth Ashok KumarSUNY Upstate Medical University, Syracuse, USA.ORCID 0000-0001-6236-2822
Jared DeckSUNY Upstate Medical University, Syracuse, USA.
Maroun Bou ZerdanSUNY Upstate Medical University, Syracuse, USA.
Michael LacombeSUNY Upstate Medical University, Syracuse, USA.
Abirami SivapiragasamSUNY Upstate Medical University, Syracuse, USA.
SUNY Upstate Medical University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation recall dermatitis is an inflammatory reaction of the skin that may infrequently occur in areas of the skin that have been previously treated with radiation therapy. This is thought to be due to a triggering agent administered after radiation therapy which leads to an acute inflammatory reaction, manifesting as a skin rash. We present the case of a 58-year-old male with recurrent invasive squamous cell carcinoma of the tongue, previously treated with chemotherapy and radiation therapy, who presented with progression of his disease. He was treated with pembrolizumab and subsequently developed a new-onset facial rash over the previously treated radiation field. The distribution of the rash was suggestive of radiation recall dermatitis. A biopsy showed dermal necrosis without evidence of dermatitis, vasculitis, or infectious process. This case highlights the incidence of a rare complication of immune checkpoint inhibitor therapy and emphasizes the need for careful monitoring for radiation recall dermatitis.

Indexed as

Carcinoma, Squamous CellExanthemaRadiodermatitisAntibodies, Monoclonal, HumanizedHumansMaleMiddle AgedNeoplasm Recurrence, LocalAntibodies, Monoclonal, Humanizedpembrolizumabdermatologyhematology oncologyradiology / imaging

Identifiers

PMID37096743
PMCPMC10134185
OpenAlexW4367020794

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.