Evidence map›Paper›PMID 37096677›Full record

ArticleJournal of cardiovascular imaging2023

Low Contrast and Low kV CTA Before Transcatheter Aortic Valve Replacement: A Systematic Review.

Spencer C Lacy, Mina M Benjamin, Mohammed Osman, Mushabbar A Syed, Menhel Kinno

Abstract read
In one paragraph

Article in Journal of cardiovascular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. SCAI Expert Consensus Statement on Alternative Access for Transcatheter Aortic Valve Replacement.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Spencer C LacyDepartment of Internal Medicine, Loyola University Medical Center, Maywood, IL, USA. spencer.c.lacy@luhs.org.ORCID https://orcid.org/0000-0002-6909-9139
Mina M BenjaminDivision of Cardiovascular Medicine, Loyola University Medical Center, Maywood, IL, USA.ORCID https://orcid.org/0000-0001-9076-2321
Mohammed OsmanKnight & Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA.ORCID https://orcid.org/0000-0001-5097-5568
Mushabbar A SyedDivision of Cardiovascular Medicine, Loyola University Medical Center, Maywood, IL, USA.ORCID https://orcid.org/0000-0002-2993-3096
Menhel KinnoDivision of Cardiovascular Medicine, Loyola University Medical Center, Maywood, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMinimizing contrast dose and radiation exposure while maintaining image quality during computed tomography angiography (CTA) for transcatheter aortic valve replacement (TAVR) is desirable, but not well established. This systematic review compares image quality for low contrast and low kV CTA versus conventional CTA in patients with aortic stenosis undergoing TAVR planning.

methodsWe performed a systematic literature review to identify clinical studies comparing imaging strategies for patients with aortic stenosis undergoing TAVR planning. The primary outcomes of image quality as assessed by the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were reported as random effects mean difference with 95% confidence interval (CI).

resultsWe included 6 studies reporting on 353 patients. There was no difference in cardiac SNR (mean difference, -1.42; 95% CI, -5.71 to 2.88; p = 0.52), cardiac CNR (mean difference, -3.83; 95% CI, -9.98 to 2.32; p = 0.22), aortic SNR (mean difference, -0.23; 95% CI, -7.83 to 7.37; p = 0.95), aortic CNR (mean difference, -3.95; 95% CI, -12.03 to 4.13; p = 0.34), and ileofemoral SNR (mean difference, -6.09; 95% CI, -13.80 to 1.62; p = 0.12) between the low dose and conventional protocols. There was a difference in ileofemoral CNR between the low dose and conventional protocols with a mean difference of -9.26 (95% CI, -15.06 to -3.46; p = 0.002). Overall, subjective image quality was similar between the 2 protocols.

conclusionsThis systematic review suggests that low contrast and low kV CTA for TAVR planning provides similar image quality to conventional CTA.

Indexed as

Aortic valveContrast mediaHeart valve prosthesis

Identifiers

PMID37096677
PMCPMC10133812

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.