Evidence map›Paper›PMID 37096420›Full record

ArticleBritish journal of neurosurgery2025

Jonathan T Dullea, Danielle Chaluts, Vikram Vasan, John W Rutland, Corey M Gill, Ethan Ellis, Yayoi Kinoshita, Russell B McBride, Joshua Bederson, Michael Donovan and 3 more

Abstract read
In one paragraph

Article in British journal of neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Jonathan T DulleaDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.ORCID 0000-0002-8018-1213
Danielle ChalutsDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Vikram VasanDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
John W RutlandDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Corey M GillDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Ethan EllisDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Yayoi KinoshitaDepartment of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Russell B McBrideDepartment of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Joshua BedersonDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Michael DonovanDepartment of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Robert SebraDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Melissa UmphlettDepartment of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Raj K ShrivastavaDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Icahn School of Medicine at Mount Sinai · USSema4 (United States) · US

Funding

Training Future Leaders in Aging ResearchT35AG067578 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALDRIDGE, MELISSA DIANE, SORIANO, RAINIER P · 2020 to 2024
$616k
NIA NIH HHS T35 AG067578
6 · The paper itself

Abstract

purposeMeningiomas occur more frequently in older adults, with the incidence rates increasing from 5.8/100,000 for adults 35-44 years old to 55.2/100,000 for those 85+. Due to the increased risk of surgical management in older adults, there is a need to characterize the risk factors for aggressive disease course to inform management decisions in this population. We therefore sought to determine age-stratified relationships between tumour genomics and recurrence after resection of atypical meningiomas.

methodsWe identified 137 primary and recurrent Grade 2 meningiomas from our existing meningioma genomic sequencing database. We examined the differential distribution of genomic alterations in those older than 65 compared to younger. We then performed an age stratified survival analysis to model recurrence for a mutation identified as differentially present.

resultsIn our cohort of 137 patients with grade 2 meningiomas, alterations in

conclusionsWe found that mutations in

Indexed as

Meningeal NeoplasmsMeningiomaMutationNeoplasm Recurrence, LocalNeurofibromin 2AdultAgedAged, 80 and overAge FactorsCohort StudiesFemaleHumansMaleMiddle AgedRisk FactorsNeurofibromin 2NF2 protein, humanDNA sequencingMeningiomamolecular genetics

Identifiers

PMID37096420
PMCPMC10598238
OpenAlexW4366990340

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.