Evidence map›Paper›PMID 37096159›Full record

Trial reportInternational journal of chronic obstructive pulmonary disease2023

Automated Oxygen Administration Alleviates Dyspnea in Patients Admitted with Acute Exacerbation of COPD: A Randomized Controlled Trial.

Charlotte Sandau, Ejvind Frausing Hansen, Thomas Jørgen Ringbæk, Thomas Kallemose, Dorthe Gaby Bove, Ingrid Poulsen, Vibeke Nørholm, Lars Pedersen, Jens Ulrik Stæhr Jensen, Charlotte Suppli Ulrik

Open access · goldAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in International journal of chronic obstructive pulmonary disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Charlotte SandauDepartment of Respiratory Medicine and Endocrinology, Pulmonary Section, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.ORCID 0000-0002-5911-4155
Ejvind Frausing HansenDepartment of Respiratory Medicine and Endocrinology, Pulmonary Section, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.ORCID 0000-0002-7269-0712
Thomas Jørgen RingbækAllergy and Lung Clinic, Elsinore, Denmark.ORCID 0000-0002-1768-6884
Thomas KallemoseDepartment of Clinical Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.ORCID 0000-0002-7356-6481
Dorthe Gaby BoveUniversity College Absalon, Centre for Nursing, Roskilde, Denmark.
Ingrid PoulsenDepartment of Clinical Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Vibeke NørholmDepartment of Clinical Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.ORCID 0000-0001-9422-4678
Lars PedersenDepartment of Respiratory Medicine and Infectious Diseases, Copenhagen University Bispebjerg Hospital, Copenhagen, Denmark.ORCID 0000-0002-5950-652X
Jens Ulrik Stæhr JensenRespiratory Medicine Section, Department of Medicine, Herlev-Gentofte Hospital, Hellerup, Denmark.ORCID 0000-0003-4036-0521
Charlotte Suppli UlrikDepartment of Respiratory Medicine and Endocrinology, Pulmonary Section, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.ORCID 0000-0001-8689-3695
Hvidovre Hospital · DKUniversity of Copenhagen · DKAarhus University · DKBispebjerg Hospital · DKDanish Lung Association · DKUniversity College Absalon · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Devices for Automated Oxygen Administration (AOA) have been developed to optimize the therapeutic benefit of oxygen supplementation. We aimed to investigate the effect of AOA on multidimensional aspects of dyspnea and as-needed consumption of opioids and benzodiazepines, as opposed to conventional oxygen therapy, in hospitalized patients with Acute Exacerbation of COPD (AECOPD). Method and Patients: A multicenter randomized controlled trial across five respiratory wards in the Capital Region of Denmark. Patients admitted with AECOPD (n=157) were allocated 1:1 to either AOA (O2matic Ltd), a closed loop device automatically delivering oxygen according to the patient's peripheral oxygen saturation (SpO Results: Of the 157 randomized patients, 127 had complete data for the intervention. The AOA reduced patients' perception of overall unpleasantness significantly on the Multidimensional Dyspnea Profile (MDP) with a difference in medians of -3 ( Conclusion: AOA reduces both breathing discomfort and physical perception of dyspnea in patients admitted with AECOPD but did not seem to impact the emotional status or other COPD symptoms.

Indexed as

Pulmonary Disease, Chronic ObstructiveDyspneaHospitalizationHumansOxygenOxygen Inhalation TherapyOxygenadmissionautomated oxygen therapyCOPDdyspneahospitalmultidimensional dyspnea profileoxygentherapy

Identifiers

PMID37096159
PMCPMC10122478
OpenAlexW4366282203

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.