Evidence map›Paper›PMID 37096155›Full record

ReviewMediators of inflammation2023

The Role of TSLP in Atopic Dermatitis: From Pathogenetic Molecule to Therapeutical Target.

Jialiang Luo, Zhengyumeng Zhu, Yumeng Zhai, Junxiang Zeng, Lei Li, Di Wang, Fan Deng, Bo Chang, Jia Zhou, Ledong Sun

Abstract readReview
In one paragraph

Review in Mediators of inflammation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Ethyl acetate fraction ofJournal of traditional and complementary medicine · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Therapeutic Potential of Isoniazid in Inflammatory Skin Diseases: A Review.Clinical, cosmetic and investigational dermatology · 2026
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. The Mechanisms of Immunoglobulin E Sensitizations in Atopic Dermatitis.Immunology and allergy clinics of North America · 2025
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Exosomes and Exosome-Mimetics for Atopic Dermatitis Therapy.Tissue engineering and regenerative medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jialiang LuoDepartment of Dermatology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0003-0070-4131
Zhengyumeng ZhuDepartment of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-1407-4516
Yumeng ZhaiDepartment of Dermatology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0006-8764-5718
Junxiang ZengDepartment of Bioinformation, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0000-2867-5243
Lei LiDepartment of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-8489-3368
Di WangDepartment of Dermatology, Dermatology Hospital of Southern Medical University, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-6326-1713
Fan DengDepartment of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-8537-2596
Bo ChangDepartment of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0004-3401-554X
Jia ZhouDepartment of Immunology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-6107-5469
Ledong SunDepartment of Dermatology, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0003-4129-4204

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a kind of chronic skin disease with inflammatory infiltration, characterized by skin barrier dysfunction, immune response dysregulation, and skin dysbiosis. Thymic stromal lymphopoietin (TSLP) acts as a regulator of immune response, positively associated with AD deterioration. Mainly secreted by keratinocytes, TSLP interacts with multiple immune cells (including dendritic cells, T cells, and mast cells), following induction of Th2-oriented immune response during the pathogenesis of AD. This article primarily focuses on the TSLP biological function, the relationship between TSLP and different cell populations, and the AD treatments targeting TSLP.

Indexed as

Dermatitis, AtopicThymic Stromal LymphopoietinCytokinesHumansKeratinocytesSkinCytokinesThymic Stromal LymphopoietinTSLP protein, mouse

Identifiers

PMID37096155
PMCPMC10122597

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.