Vitelliform maculopathy in MELAS syndrome.

Cody Jahrig, Cristy A Ku, Molly Marra, Mark E Pennesi, Paul Yang

Open access · goldAbstract readCase Reports

In one paragraph

Article in American journal of ophthalmology case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.5field-weighted citation impact, top 34% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

Evolution of vitelliform maculopathy in a pediatric patient with a homozygousAmerican journal of ophthalmology case reports · 2025
Article
Multifocal vitelliform lesions associated with mitochondrial retinopathy.American journal of ophthalmology case reports · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Cody JahrigDepartment of Medicine, Nassau University Medical Center, East Meadow, NY, United States.

Cristy A KuDepartment of Ophthalmology, University of California Davis, Sacramento, CA, United States.

Molly MarraDepartment of Ophthalmology, Casey Eye Institute, Oregon Health & Science University (OHSU), Portland, OR, United States.

Mark E PennesiDepartment of Ophthalmology, Casey Eye Institute, Oregon Health & Science University (OHSU), Portland, OR, United States.

Paul YangDepartment of Ophthalmology, Casey Eye Institute, Oregon Health & Science University (OHSU), Portland, OR, United States.

Oregon Health & Science University · USNassau University Medical Center · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We present a unique case of foveomacular vitelliform lesions in a patient with metabolic encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS). Observations: After performing large panel next generation sequencing genetic testing, there was no likely alternative genetic etiology for vitelliform maculopathy in this patient. Conclusions and Importance: We present a rare case of a visually asymptomatic pediatric patient with MELAS and vitelliform maculopathy, which may be part of the spectrum of retinal manifestations in MELAS. Pediatric-onset vitelliform maculopathy in MELAS may be under-diagnosed due to its asymptomatic nature. Given the known risk of choroidal neovascularization in vitelliform maculopathy, it is important to identify these patients for proper surveillance.

Indexed as

Macular dystrophyMaculopathyMELASVitelliform

Identifiers

PMID37096132

DOI10.1016/j.ajoc.2023.101842

PMCPMC10121376

OpenAlexW4362671284

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.