Evidence map›Paper›PMID 37096041›Full record

ArticleiScience2023

Combing fecal microbial community data to identify consistent obesity-specific microbial signatures and shared metabolic pathways.

Yu Lin, Zhilu Xu, Yun Kit Yeoh, Hein Min Tun, Wenli Huang, Wei Jiang, Francis Ka Leung Chan, Siew Chien Ng

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

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  17. Frontiers in microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yu LinMicrobiota I-Center (MagIC), Hong Kong SAR, China.
Zhilu XuMicrobiota I-Center (MagIC), Hong Kong SAR, China.
Yun Kit YeohMicrobiota I-Center (MagIC), Hong Kong SAR, China.
Hein Min TunMicrobiota I-Center (MagIC), Hong Kong SAR, China.
Wenli HuangMicrobiota I-Center (MagIC), Hong Kong SAR, China.
Wei JiangMicrobiota I-Center (MagIC), Hong Kong SAR, China.
Francis Ka Leung ChanMicrobiota I-Center (MagIC), Hong Kong SAR, China.
Siew Chien NgMicrobiota I-Center (MagIC), Hong Kong SAR, China.
Chinese University of Hong Kong · CNHong Kong Jockey Club · CN

Funding

Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
Pharmacogenomics of CVD risk ReductionU01GM074518 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI SHULDINER, ALAN R. · 2005 to 2009
$7.3M
The Thrifty Microbiome: The Role of the Gut Microbiota in Obesity in the AmishUH2DK083982 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI FRASER, CLAIRE M., SHULDINER, ALAN R. · 2009 to 2010
$1.3M
NIDDK NIH HHS P30 DK072488NIDDK NIH HHS UH2 DK083982NIGMS NIH HHS U01 GM074518
6 · The paper itself

Abstract

Obesity is associated with altered gut microbiome composition but data across different populations remain inconsistent. We meta-analyzed publicly available 16S-rRNA sequence datasets from 18 different studies and identified differentially abundant taxa and functional pathways of the obese gut microbiome. Most differentially abundant genera (

Indexed as

Health sciencesMachine learningMicrobiome

Identifiers

PMID37096041
PMCPMC10122048
OpenAlexW4353048134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.