Evidence map›Paper›PMID 37095701›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2023

Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.

Wei Wang, Yun Gu, Hao Ni, Qiuying Quan, Lingchuan Guo

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Identification of Tumor SuppressiveInternational journal of molecular sciences · 2024
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wei WangDepartment of Pathology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Yun GuDepartment of Pathology, Women's Hospital of Nanjing Medical University (Nanjing Maternity and Child Health Care Hospital), Nanjing 210004, China.
Hao NiDepartment of Pathology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Qiuying QuanDepartment of Pathology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Lingchuan GuoDepartment of Pathology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.ORCID 0000-0002-1028-9296
Soochow University · CNNanjing Maternity and Child Health Care Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer is the most lethal gynecological tumor in women worldwide. FAM111B (family with sequence similarity 111 member B) is an oncoprotein associated with multiple cancers, but its biological functions in ovarian cancer remain elusive. In this study, FAM111B was overexpressed in ovarian cancer tissues and cell lines. Functional studies

Indexed as

Ovarian NeoplasmsProto-Oncogene Proteins c-aktAnimalsApoptosisCaspasesCell Cycle ProteinsCell Line, TumorCell MovementCell ProliferationFemaleHumansTumor Suppressor Protein p53CaspasesCell Cycle ProteinsFAM111B protein, humanProto-Oncogene Proteins c-aktTumor Suppressor Protein p53apoptosisFAM111Bovarian cancerp53p-AKTtumor growth

Identifiers

PMID37095701
PMCPMC10581161
OpenAlexW4366989185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.