ArticleThe Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association2024
Cancer disparities in Appalachian Kentucky.
Article in The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The trial behind it
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Who cites it
14 citing papers in PubMed.
- Missed Clinic Appointments for Human Papillomavirus-Related Oropharyngeal Cancer.Laryngoscope investigative otolaryngology · 2026Article
- Peer-Led Cancer Education Intervention in Appalachian Kentucky: Evaluating Effects on Participants' Cancer Knowledge and Perspectives.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Article
- Cancer Screening in Appalachia: A Common-Sense Approach.International journal of behavioral medicine · 2025Article
- Educating and Retaining the Cancer-Focused Biomedical Workforce from Rural Appalachian Kentucky: The Impact of Experiential Learning and Scholarship Funding.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- Examining Geographic Disparity: Variation in Cancer Outcomes Within Appalachia.Journal of the American College of Surgeons · 2025Article
- Head and Neck Cancer Mortality in the Appalachian Region.JAMA otolaryngology-- head & neck surgery · 2025Article
- Multilevel Mentorship Prepares Youth for the Oncology Workforce in Appalachian Kentucky.Health promotion practice · 2025Article
- Geospatial Analysis of Breast Cancer Incidence, Mortality, and Access to Screening in Rural and Appalachian Virginia.Journal of Appalachian health · 2025Article
- Prognostic Significance and Treatment Response Associations of Genetic Mutations in Chronic Myelomonocytic Leukemia: A Retrospective Cohort Study.Biomedicines · 2024Article
- Appalachia's worsening disparities in cancer mortality should be viewed as a regional manifestation of widening global disparities in health outcomes rather than a uniquely American phenomena.Lancet regional health. Americas · 2024Article
- Human papillomavirus circulating tumor DNA assays as a mechanism for head and neck cancer equity in rural regions of the United States.Frontiers in oncology · 2024Review
- Impact of a Cancer Education Curriculum on Appalachian Kentucky Middle and High School Students.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023Article
- A Qualitative Study of Participant Perceptions of a Cancer Research Education Program.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023Article
- Leveraging Machine Learning Models to Explore Disparities in Prostate Cancer Diagnosis, Treatment, and Survival.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeCancer is the second leading cause of death in the United States, and the disease burden is elevated in Appalachian Kentucky, due in part to health behaviors and inequities in social determinants of health. This study's goal was to evaluate Appalachian Kentucky's cancer burden compared to non-Appalachian Kentucky, and Kentucky compared to the United States (excluding Kentucky).
methodsThe following data were analyzed: annual all-cause and all-site cancer mortality rates from 1968 to 2018; 5-year all-site and site-specific cancer incidence and mortality rates from 2014 to 2018; aggregated screening and risk factor data from 2016 to 2018 for the United States (excluding Kentucky), Kentucky, non-Appalachian Kentucky, and Appalachian Kentucky; and human papilloma virus vaccination prevalence by sex from 2018 for the United States and Kentucky.
findingsSince 1968, the United States has experienced a large decrease in all-cause and cancer mortality, but the reduction in Kentucky has been smaller and slower, driven by even smaller and slower reductions within Appalachian Kentucky. Appalachian Kentucky has higher overall cancer incidence and mortality rates and higher rates for several site-specific cancers compared to non-Appalachian Kentucky. Contributing factors include screening rate disparities and increased rates of obesity and smoking.
conclusionsAppalachian Kentucky has experienced persistent cancer disparities, including elevated all-cause and cancer mortality rates for 50+ years, widening the gap between this region and the rest of the country. In addition to addressing social determinants of health, increased efforts aimed at improving health behaviors and increased access to health care resources could help reduce this disparity.
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