Evidence map›Paper›PMID 37095516›Full record

ArticleBiomedical engineering online2023

Application effect of an artificial intelligence-based fundus screening system: evaluation in a clinical setting and population screening.

Shujuan Cao, Rongpei Zhang, Aixin Jiang, Mayila Kuerban, Aizezi Wumaier, Jianhua Wu, Kaihua Xie, Mireayi Aizezi, Abudurexiti Tuersun, Xuanwei Liang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical engineering online, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Shujuan Cao *Ophthalmologic Center, The Affiliated Kashi Hospital of Sun Yat-sen University, The First People's Hospital of Kashi Prefecture, Kashi, 844000, China.
Rongpei Zhang *State Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.ORCID http://orcid.org/0000-0001-5015-9907
Aixin JiangOphthalmologic Center, The Affiliated Kashi Hospital of Sun Yat-sen University, The First People's Hospital of Kashi Prefecture, Kashi, 844000, China.
Mayila KuerbanOphthalmologic Center, The Affiliated Kashi Hospital of Sun Yat-sen University, The First People's Hospital of Kashi Prefecture, Kashi, 844000, China.
Aizezi WumaierOphthalmologic Center, The Affiliated Kashi Hospital of Sun Yat-sen University, The First People's Hospital of Kashi Prefecture, Kashi, 844000, China.
Jianhua WuOphthalmologic Center, The Affiliated Kashi Hospital of Sun Yat-sen University, The First People's Hospital of Kashi Prefecture, Kashi, 844000, China.
Kaihua XieOphthalmologic Center, The Affiliated Kashi Hospital of Sun Yat-sen University, The First People's Hospital of Kashi Prefecture, Kashi, 844000, China.
Mireayi AizeziOphthalmologic Center, The Affiliated Kashi Hospital of Sun Yat-sen University, The First People's Hospital of Kashi Prefecture, Kashi, 844000, China.
Abudurexiti TuersunOphthalmologic Center, The Affiliated Kashi Hospital of Sun Yat-sen University, The First People's Hospital of Kashi Prefecture, Kashi, 844000, China.
Xuanwei LiangState Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China. liangxuanwei@163.com.
Rongxin ChenState Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China. rongxinchan@foxmail.com.ORCID http://orcid.org/0000-0003-4867-8331
Sun Yat-sen University · CNMitsubishi Group (Japan) · JP

Funding

Natural Science Foundation of Xinjiang Uygur Autonomous Region 2019D01C004Science and Technology Program of Guangzhou 202102020736The Pearl River Scholar Tianshan Talent Cooperation's Expert Studio Innovation Team KDYY202018Xinjiang Uygur Autonomous Region Innovation Environment (Talents, Bases) Special Project (Special Talent Project-Tianshan Youth Project) 2019Q145
6 · The paper itself

Abstract

backgroundTo investigate the application effect of artificial intelligence (AI)-based fundus screening system in real-world clinical environment.

methodsA total of 637 color fundus images were included in the analysis of the application of the AI-based fundus screening system in the clinical environment and 20,355 images were analyzed in the population screening.

resultsThe AI-based fundus screening system demonstrated superior diagnostic effectiveness for diabetic retinopathy (DR), retinal vein occlusion (RVO) and pathological myopia (PM) according to gold standard referral. The sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of three fundus abnormalities were greater (all > 80%) than those for age-related macular degeneration (ARMD), referable glaucoma and other abnormalities. The percentages of different diagnostic conditions were similar in both the clinical environment and the population screening.

conclusionsIn a real-world setting, our AI-based fundus screening system could detect 7 conditions, with better performance for DR, RVO and PM. Testing in the clinical environment and through population screening demonstrated the clinical utility of our AI-based fundus screening system in the early detection of ocular fundus abnormalities and the prevention of blindness.

Indexed as

Diabetic RetinopathyGlaucomaMacular DegenerationArtificial IntelligenceFundus OculiHumansMass ScreeningArtificial intelligenceColor fundus photographyEarly screeningOcular fundus abnormalitiesPrevention of blindness

Identifiers

PMID37095516
PMCPMC10127070
OpenAlexW4366825494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.