Evidence map›Paper›PMID 37095482›Full record

ArticleBMC pediatrics2023

Clinical profile of children under 5 years of age with rotavirus diarrhoea in a hospital setting in Kisangani, DRC, after the introduction of the rotavirus vaccine, a cross-sectional study.

Didier Gbebangi-Manzemu, Véronique Muyobela Kampunzu, Hortense Malikidogo Vanzwa, Mupenzi Mumbere, Gaspard Mande Bukaka, Bibi Batoko Likele, Emmanuel Tebandite Kasai, Benoit Mbiya Mukinayi, Serge Tonen-Wolyec, Nestor Ngbonda Dauly and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Didier Gbebangi-ManzemuDepartment of Paediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo. didiergbebangi@gmail.com.
Véronique Muyobela KampunzuDepartment of Paediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Hortense Malikidogo VanzwaDepartment of Paediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Mupenzi MumbereDepartment of Paediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Gaspard Mande BukakaDepartment of Paediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Bibi Batoko LikeleDepartment of Paediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Emmanuel Tebandite KasaiDepartment of Paediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Benoit Mbiya MukinayiDepartment of Paediatrics, Faculty of Medicine, University of Mbujimayi, Mbuji-Mayi, Democratic Republic of the Congo.
Serge Tonen-WolyecDepartment of Internal Medicine, Faculty of Medicine, University of Bunia, Bunia, Democratic Republic of the Congo.
Nestor Ngbonda DaulyDepartment of Paediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Jean Pierre Alworong'a OparaDepartment of Paediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Université de Kisangani · CDUniversité Catholique du Graben · CDUniversity of Mbuji Mayi · CD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Democratic Republic of the Congo (DRC) is one of the countries with the highest rotavirus mortality rate in the world. The aim of this study was to describe the clinical features of rotavirus infection after the introduction of rotavirus vaccination of children in the city of Kisangani, DRC.

methodsWe conducted a cross-sectional study of acute diarrhoea in children under 5 years of age admitted to 4 hospitals in Kisangani, DRC. Rotavirus was detected in children's stools by an immuno-chromatographic antigenic rapid diagnostic test.

resultsA total of 165 children under 5 years of age were included in the study. We obtained 59 cases of rotavirus infection, or 36% CI95 [27, 45]. The majority of children with rotavirus infection were unvaccinated (36 cases) and had watery diarrhoea (47 cases), of high frequency per day/per admission 9.6 ± 3.4 and accompanied by severe dehydration (30 cases). A statistically significant difference in mean Vesikari score was observed between unvaccinated and vaccinated children (12.7 vs 10.7 p-value 0.024).

conclusionRotavirus infection in hospitalized children under 5 years of age is characterized by a severe clinical manifestation. Epidemiological surveillance is needed to identify risk factors associated with the infection.

Indexed as

RotavirusRotavirus InfectionsRotavirus VaccinesChildChild, PreschoolCross-Sectional StudiesDemocratic Republic of the CongoDiarrheaHospitalsHumansInfantRotavirus VaccinesAcute diarrhoeaChildren under 5KisanganiRotavirus

Identifiers

PMID37095482
PMCPMC10123467
OpenAlexW4366975013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.