Evidence map›Paper›PMID 37095368›Full record

ArticleMolecular neurobiology2023

Rat Hair Metabolomics Analysis Reveals Perturbations of Unsaturated Fatty Acid Biosynthesis, Phenylalanine, and Arachidonic Acid Metabolism Pathways Are Associated with Amyloid-β-Induced Cognitive Deficits.

Tian-Hoe Tan, Shih-Wen Li, Chih-Wei Chang, Yuan-Chih Chen, Yu-Hsuan Liu, Jui-Ti Ma, Ching-Ping Chang, Pao-Chi Liao

Open access · hybridAbstract read
In one paragraph

Article in Molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tian-Hoe Tan *Department of Emergency Medicine, Chi Mei Medical Center, Tainan, 710, Taiwan.
Shih-Wen Li *Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan, 70428, Taiwan.
Chih-Wei ChangDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan, 70428, Taiwan.
Yuan-Chih ChenDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan, 70428, Taiwan.
Yu-Hsuan LiuDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan, 70428, Taiwan.
Jui-Ti MaDepartment of Medical Research, Chi Mei Medical Center, No. 901, Zhonghua Rd., Yongkang Dist., Tainan, 710, Taiwan.
Ching-Ping ChangDepartment of Medical Research, Chi Mei Medical Center, No. 901, Zhonghua Rd., Yongkang Dist., Tainan, 710, Taiwan. jessica.cpchang@gmail.com.ORCID http://orcid.org/0000-0003-0890-9414
Pao-Chi LiaoDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, 138 Sheng-Li Road, Tainan, 70428, Taiwan. liaopc@mail.ncku.edu.tw.ORCID http://orcid.org/0000-0001-8510-9870
Chi Mei Medical Center · TWNational Cheng Kung University · TW

Funding

Chi Mei Medical Center CMFHR11117Chi Mei Medical Center CMNCKU 11013Ministry of Science and Technology, Taiwan MOST109-2113-M-006-015Ministry of Science and Technology, Taiwan MOST110-2113-M-006-014Ministry of Science and Technology, Taiwan MOST111-2113-M-006-011
6 · The paper itself

Abstract

Hair is a noninvasive valuable biospecimen for the long-term assessment of endogenous metabolic disturbance. Whether the hair is suitable for identifying biomarkers of the Alzheimer's disease (AD) process remains unknown. We aim to investigate the metabolism changes in hair after β-amyloid (Aβ

Indexed as

Alzheimer DiseaseCognitive DysfunctionCortisoneAmyloid beta-PeptidesAnimalsArachidonic AcidBiomarkersCognitionFatty Acids, UnsaturatedHairMetabolomicsPhenylalanineRatsAmyloid beta-PeptidesArachidonic AcidBiomarkersCortisoneFatty Acids, UnsaturatedPhenylalanineArachidonic acidHair metabolismL-PhenylalanineTargeted/untargeted metabolomicsUnsaturated fatty acid

Identifiers

PMID37095368
PMCPMC10293421
OpenAlexW4366815063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.