ArticleClinical and experimental nephrology2023
Prognostic impact of renal sinus fat accumulation in patients with chronic kidney disease.
Article in Clinical and experimental nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 12 citations in OpenAlex.
- Visceral Adiposity and Renal Health: From Pathophysiological Mechanisms to Novel Therapeutic Strategies.Journal of clinical medicine · 2026Review
- Mechanisms of Obesity-Related Kidney Disease: From Adipose Depot Biology to the Chymase-Aldosterone and Ghrelin-Leptin Axes.Biomolecules · 2026Review
- Leveraging CT-derived chronic imaging signatures for acute kidney injury evaluation.Scientific reports · 2026Article
- Visceral Adipose Tissue Alters Podometrics and Renal Compensation After Uninephrectomy.Kidney international reports · 2026Article
- Waist-to-height ratio as a non-invasive marker of renal sinus fat: a MRI-based cohort study.International journal of obesity (2005) · 2026Article
- Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function.Kidney international · 2026Article
- Ectopic lipid deposition in kidney diseases: mechanisms in specific cell types and therapeutic strategies.Frontiers in endocrinology · 2026Review
- Depot-specific metabolic and inflammatory profiles in perirenal and renal sinus adipose tissue.Molecular medicine (Cambridge, Mass.) · 2025Article
- Renal ectopic fat deposition and hemodynamics in type 2 diabetes mellitus assessment with magnetic resonance imaging.Insights into imaging · 2025Article
- Metabolic Dysfunction-Associated Steatotic Liver Disease: Pathogenetic Links to Cardiovascular Risk.Biomolecules · 2025Review
- Association of visceral adipose tissue with albuminuria and interaction between visceral adiposity and diabetes on albuminuria.Acta diabetologica · 2024Article
- Association Between Renal Sinus Fat and Cardiometabolic and Renin-Angiotensin System Parameters in Primary Aldosteronism.Journal of the Endocrine Society · 2023Article
- Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity is associated with the development and progression of chronic kidney disease (CKD). In the general population, the amount of renal sinus fat was associated with hypertension and renal impairment. However, its impact upon those with CKD remains uncertain.
methodsWe prospectively included CKD patients who underwent renal biopsy and simultaneously measured their renal sinus fat volume. The association between the percentage of renal sinus fat volume, which was adjusted by kidney volume, and renal outcomes was investigated.
resultsA total of 56 patients (median 55 years old, 35 men) were included. Among baseline characteristics, age and visceral fat volume were positively correlated with the percentage of renal sinus fat volume (p < 0.05). The percentage of renal sinus fat volume was associated with hypertension (p < 0.01) and tended to be associated with max glomerular diameter (p = 0.078) and urine angiotensinogen creatinine ratio (p = 0.064) after adjustment with several clinical factors. The percentage of renal sinus fat volume was significantly associated with a future > 50% decline in estimated glomerular filtration rate (p < 0.05).
conclusionsAmong those with CKD who required renal biopsy, the amount of renal sinus fat was associated with poor renal outcomes accompanied by systemic hypertension.
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