Evidence map›Paper›PMID 37095278›Full record

ArticleAnnals of biomedical engineering2023

Evaluating the Intracranial Pressure Biofidelity and Response Repeatability of a Physical Head-Brain Model in Frontal Impacts.

Yizhao Li, Paris Vakiel, Kevin Adanty, Simon Ouellet, Albert H Vette, Donald Raboud, Christopher R Dennison

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In one paragraph

Article in Annals of biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yizhao LiDepartment of Mechanical Engineering, University of Alberta, Edmonton, AB, T6G 1H9, Canada.
Paris VakielDepartment of Mechanical Engineering, University of Victoria, Victoria, BC, V8P 5C2, Canada. pvakiel@uvic.ca.ORCID http://orcid.org/0000-0001-8134-198X
Kevin AdantyDepartment of Mechanical Engineering, University of Alberta, Edmonton, AB, T6G 1H9, Canada.
Simon OuelletWeapons Effects and Protection Section, Defence R&D Valcartier Research Center, Quebec, Canada.
Albert H VetteDepartment of Mechanical Engineering, University of Alberta, Edmonton, AB, T6G 1H9, Canada.
Donald RaboudDepartment of Mechanical Engineering, University of Alberta, Edmonton, AB, T6G 1H9, Canada.
Christopher R DennisonDepartment of Mechanical Engineering, University of Victoria, Victoria, BC, V8P 5C2, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Headforms are widely used in head injury research and headgear assessment. Common headforms are limited to replicating global head kinematics, although intracranial responses are crucial to understanding brain injuries. This study aimed to evaluate the biofidelity of intracranial pressure (ICP) and the repeatability of head kinematics and ICP of an advanced headform subjected to frontal impacts. Pendulum impacts were performed on the headform using various impact velocities (1-5 m/s) and impactor surfaces (vinyl nitrile 600 foam, PCM746 urethane, and steel) to simulate a previous cadaveric experiment. Head linear accelerations and angular rates in three axes, cerebrospinal fluid ICP (CSFP), and intraparenchymal ICP (IPP) at the front, side, and back of the head were measured. The head kinematics, CSFP, and IPP demonstrated acceptable repeatability with coefficients of variation generally being less than 10%. The BIPED front CSFP peaks and back negative peaks were within the range of the scaled cadaver data (between the minimum and maximum values reported by Nahum et al.), while side CSFPs were 30.9-92.1% greater than the cadaver data. CORrelation and Analysis (CORA) ratings evaluating the closeness of two time histories demonstrated good biofidelity of the front CSFP (0.68-0.72), while the ratings for the side (0.44-0.70) and back CSFP (0.27-0.66) showed a large variation. The BIPED CSFP at each side was linearly related to head linear accelerations with coefficients of determination greater than 0.96. The slopes for the BIPED front and back CSFP-acceleration linear trendlines were not significantly different from cadaver data, whereas the slope for the side CSFP was significantly greater than cadaver data. This study informs future applications and improvements of a novel head surrogate.

Indexed as

Craniocerebral TraumaIntracranial PressureAccelerationBiomechanical PhenomenaBrainCadaverHeadHumansCerebrospinal fluid ICPHeadformHead injuryIntraparenchymal ICPKinematicsPendulum impact

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.