Evidence map›Paper›PMID 37095231›Full record

ReviewBone marrow transplantation2023

Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a refined classification from the European society for blood and marrow transplantation (EBMT).

Mohamad Mohty, Florent Malard, Ahmed S Alaskar, Mahmoud Aljurf, Mutlu Arat, Peter Bader, Frederic Baron, Ali Bazarbachi, Didier Blaise, Eolia Brissot and 15 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Bone marrow transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

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  20. Pericardial Effusion Post Hematopoietic Stem Cell Transplant: A Life-Threatening Complication with Myriad Causes.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Mohamad Mohty *Hematology Department, Hôpital Saint-Antoine, and Université Pierre & Marie Curie, Paris, France. mohamad.mohty@inserm.fr.ORCID http://orcid.org/0000-0002-7264-808X
Florent Malard *Hematology Department, Hôpital Saint-Antoine, and Université Pierre & Marie Curie, Paris, France.ORCID http://orcid.org/0000-0002-3474-0002
Ahmed S Alaskar *King Abdullah International Medical Research Center/King Saud Bin Abdulaziz University for Health Sciences, Dept. of Oncology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.ORCID http://orcid.org/0000-0002-0648-3256
Mahmoud Aljurf *King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.ORCID http://orcid.org/0000-0003-3942-7370
Mutlu Arat *Sisli Florence Nightingale Hospital, HSCT Unit, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-2039-8557
Peter Bader *Division for Stem Cell Transplantation and Immunology, Department for Children and Adolescents, University Hospital, Goethe University, Frankfurt/Main, Germany.ORCID http://orcid.org/0000-0003-4554-0265
Frederic Baron *Department of Hematology, University of Liege, Liege, Belgium.ORCID http://orcid.org/0000-0002-2944-3812
Ali Bazarbachi *Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.ORCID http://orcid.org/0000-0002-7171-4997
Didier Blaise *Aix-Marseille Univ, MSC Lab, Institut Paoli-Calmettes, Department of Hematology, Marseille, France.ORCID http://orcid.org/0000-0002-5684-9447
Eolia Brissot *Hematology Department, Hôpital Saint-Antoine, and Université Pierre & Marie Curie, Paris, France.
Fabio Ciceri *San Raffaele Scientific Institute, Hematology and Bone marrow Transplantation Unit, Milan, Italy.ORCID http://orcid.org/0000-0003-0873-0123
Selim Corbacioglu *Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, University of Regensburg, Regensburg, Germany.
Jean-Hugues Dalle *Department of Hematology and Immunology, Hospital Robert Debre, Paris 7-Paris Diderot University, Paris, France.ORCID http://orcid.org/0000-0002-8406-0793
Fiona Dignan *Department of Clinical Haematology, Manchester University NHS Foundation Trust, Manchester, UK.
Anne Huynh *Hematology Department, Institut Universitaire du Cancer Toulouse - Oncopole, Toulouse, France.
Michelle Kenyon *Department of Haematology, King's College Hospital, London, UK.ORCID http://orcid.org/0000-0002-1859-6178
Arnon Nagler *Hematology and Bone Marrow Transplantation, Chaim Sheba Medical center, Tel-Hashomer, Israel.
Antonio Pagliuca *Department of Haematology, King's College Hospital, London, UK.
Zinaida Perić *Department of Hematology, University Hospital Centre Zagreb and School of Medicine, University of Zagreb, Zagreb, Croatia.
Paul G Richardson *Division of Hematology, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-7426-8865
Annalisa Ruggeri *San Raffaele Scientific Institute, Hematology and Bone marrow Transplantation Unit, Milan, Italy.ORCID http://orcid.org/0000-0002-7261-2765
Tapani Ruutu *Clinical Research Institute, Helsinki University Hospital, Helsinki, Finland.
Ibrahim Yakoub-Agha *CHU de Lille, Univ Lille, INSERM U1286, Infinite, 59000, Lille, France.ORCID http://orcid.org/0000-0003-4524-8782
Rafael F Duarte *Department of Hematology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
Enric Carreras *Josep Carreras Foundation & Leukemia Research Institute, (Hospital Clínic/Barcelona University Campus), Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation (HCT). A new definition for diagnosis, and a severity grading system for SOS/VOD in adult patients, was reported a few years ago on behalf of the European Society for Blood and Marrow Transplantation (EBMT). The aim of this work is to update knowledge regarding diagnosis and severity assessment of SOS/VOD in adult patients, and also its pathophysiology and treatment. In particular, we now propose to refine the previous classification and distinguish probable, clinical and proven SOS/VOD at diagnosis. We also provide an accurate definition of multiorgan dysfunction (MOD) for SOS/VOD severity grading based on Sequential Organ Failure Assessment (SOFA) score.

Indexed as

Hematopoietic Stem Cell TransplantationHepatic Veno-Occlusive DiseaseVascular DiseasesAdultBone MarrowHumansSyndrome

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.