Evidence map›Paper›PMID 37095177›Full record

ArticleCommunications medicine2023

Adaptive spectroscopic visible-light optical coherence tomography for clinical retinal oximetry.

Ian Rubinoff, Roman V Kuranov, Raymond Fang, Zeinab Ghassabi, Yuanbo Wang, Lisa Beckmann, David A Miller, Gadi Wollstein, Hiroshi Ishikawa, Joel S Schuman and 1 more

Open access · goldAbstract read
In one paragraph

Article in Communications medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Development of an optically emulated computed tomography scanner for college education.Visual computing for industry, biomedicine, and art · 2026
    Article
  6. Review
  7. Refractive Index-Corrected Light-Sheet Microscopy for Macro-View Cardiovascular Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  8. Review
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  10. Review
  11. Article
  12. Article
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  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Quantitative Optical Imaging of Oxygen in Brain Vasculature.The journal of physical chemistry. B · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ian RubinoffDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Roman V KuranovDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Raymond FangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Zeinab GhassabiDepartment of Ophthalmology, New York University, New York, NY, 10017, USA.
Yuanbo WangCurrently with Department of Ophthalmology, Oregon Health & Science University, Portland, OR, 97239, USA.
Lisa BeckmannDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
David A MillerDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Gadi WollsteinDepartment of Ophthalmology, New York University, New York, NY, 10017, USA.
Hiroshi IshikawaDepartment of Ophthalmology, New York University, New York, NY, 10017, USA.
Joel S SchumanDepartment of Ophthalmology, New York University, New York, NY, 10017, USA.ORCID http://orcid.org/0000-0002-8885-3766
Hao F ZhangDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA. hfzhang@northwestern.edu.ORCID http://orcid.org/0000-0001-5089-1196
Northwestern University · USNew York University · USOregon Health & Science University · US

Funding

Novel Glaucoma Diagnostics for Structure and Function - Renewal - 1R01EY013178 · NEI · WILLS EYE HEALTH SYSTEM · PI Joel S Schuman · 2000 to 2026
$17.5M
ER Stress and Diabetic RetinopathyR01EY019949 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ZHANG, SARAH X · 2010 to 2023
$5.5M
Clinical glaucoma management enabled by visible-light OCTU01EY033001 · NEI · NORTHWESTERN UNIVERSITY · PI SCHUMAN, JOEL S, ZHANG, HAO F · 2021 to 2025
$3.2M
Visible-light optical coherence tomography for clinical glaucoma managementR44EY026466 · NEI · OPTICENT, INC. · PI KURANOV, ROMAN · 2018 to 2023
$2.7M
Investigating oxygen metabolism in diabetic retinopathyR01EY026078 · NEI · NORTHWESTERN UNIVERSITY · PI SHEIBANI, NADER, ZHANG, HAO F · 2016 to 2020
$2.3M
Investigating nanoscale neuronal damages in early glaucoma towards clinical optical detectionR01EY029121 · NEI · NORTHWESTERN UNIVERSITY · PI LIU, XIAORONG, ZHANG, HAO F · 2018 to 2021
$2.0M
Physical Genomics and Engineering Training ProgramT32GM142604 · NIGMS · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM · 2021 to 2025
$1.9M
Visual Sciences T32T32EY025202 · NEI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Gregory William Schwartz · 2015 to 2026
$1.4M
NEI NIH HHS R01 EY013178NEI NIH HHS R01 EY019949NEI NIH HHS R01 EY026078NEI NIH HHS R01 EY029121NEI NIH HHS R44 EY026466NEI NIH HHS T32 EY025202NEI NIH HHS U01 EY033001NIGMS NIH HHS T32 GM142604
6 · The paper itself

Abstract

backgroundRetinal oxygen saturation (sO

methodsWe develop an adaptive spectroscopic vis-OCT (ADS-vis-OCT) technique that can adaptively remove SCs and accurately measure sO

resultsIn ex vivo blood phantoms, ADS-vis-OCT agrees with a blood gas machine with only a 1% bias in samples with sO

conclusionsADS-vis-OCT effectively removes SCs from human images, yielding accurate and repeatable sO

Identifiers

PMID37095177
PMCPMC10126115
OpenAlexW4366975133

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.