Evidence map›Paper›PMID 37095092›Full record

ArticleNature communications2023

Parasubthalamic calretinin neurons modulate wakefulness associated with exploration in male mice.

Han Guo, Jian-Bo Jiang, Wei Xu, Mu-Tian Zhang, Hui Chen, Huan-Ying Shi, Lu Wang, Miao He, Michael Lazarus, Shan-Qun Li and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  14. Review
  15. Mouse parasubthalamicbioRxiv : the preprint server for biology · 2024
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Han Guo *Department of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.ORCID 0000-0002-2492-5564
Jian-Bo Jiang *Department of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.ORCID 0000-0002-0127-7306
Wei XuDepartment of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.ORCID 0000-0001-5236-0188
Mu-Tian ZhangDepartment of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.ORCID 0000-0003-3769-2795
Hui ChenDepartment of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.
Huan-Ying ShiDepartment of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Lu WangDepartment of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.ORCID 0000-0002-4244-5687
Miao HeDepartment of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China.ORCID 0000-0003-0731-6801
Michael LazarusInternational Institute for Integrative Sleep Medicine (WPIIIIS), University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.ORCID 0000-0003-4700-7894
Shan-Qun LiDepartment of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. lsq18616880856@163.com.ORCID 0000-0002-8096-9780
Zhi-Li HuangDepartment of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China. huangzl@fudan.edu.cn.ORCID 0000-0001-9359-1150
Wei-Min QuDepartment of Pharmacology, School of Basic Medical Sciences; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, and Institutes of Brain Science, Fudan University, Shanghai, 200032, China. quweimin@fudan.edu.cn.ORCID 0000-0002-0251-5214

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The parasubthalamic nucleus (PSTN) is considered to be involved in motivation, feeding and hunting, all of which are highly depending on wakefulness. However, the roles and underlying neural circuits of the PSTN in wakefulness remain unclear. Neurons expressing calretinin (CR) account for the majority of PSTN neurons. In this study in male mice, fiber photometry recordings showed that the activity of PSTN

Indexed as

NeuronsWakefulnessAnimalsArousalCalbindin 2MaleMiceSleepSleep, REMCalbindin 2

Identifiers

PMID37095092
PMCPMC10126000

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.